Detalhe da pesquisa
1.
Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine.
Annu Rev Pharmacol Toxicol
; 62: 427-446, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34499525
2.
Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension.
Circ Res
; 131(9): e102-e119, 2022 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36164973
3.
Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903.
J Biol Chem
; 298(2): 101546, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34999117
4.
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.
Liver Int
; 43(9): 2026-2038, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349903
5.
Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat.
Circ Res
; 129(7): 720-734, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34420367
6.
Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
EMBO Rep
; 22(5): e50767, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33934497
7.
An ex vivo perfused ventilated murine lung model suggests lack of acute pulmonary toxicity of the potential novel anticancer agent (-)-englerin A.
Arch Toxicol
; 96(4): 1055-1063, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165752
8.
Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension.
Biophys J
; 120(8): 1510-1521, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582135
9.
Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure.
Biophys J
; 120(8): 1343-1356, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582137
10.
Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Circulation
; 141(3): 199-216, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31906693
11.
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
Am J Physiol Cell Physiol
; 319(1): C64-C74, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32401607
12.
Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion.
J Biol Chem
; 294(46): 17395-17408, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586031
13.
Force Sensing by Piezo Channels in Cardiovascular Health and Disease.
Arterioscler Thromb Vasc Biol
; 39(11): 2228-2239, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533470
14.
Piezo1 integration of vascular architecture with physiological force.
Nature
; 515(7526): 279-282, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25119035
15.
ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension.
Physiology (Bethesda)
; 33(4): 261-268, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29897302
16.
Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop.
Circ Res
; 120(5): 784-798, 2017 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27920123
17.
Endothelial Piezo1 channels as sensors of exercise.
J Physiol
; 596(6): 979-984, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29194632
18.
(-)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase.
J Biol Chem
; 292(2): 723-731, 2017 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875305
19.
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
J Biol Chem
; 292(20): 8158-8173, 2017 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325835
20.
RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.
Blood
; 136(1): 140-144, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32305040