Pesquisa | Biblioteca Virtual em Saúde Fiocruz

1.

SALL4 controls cell fate in response to DNA base composition.

Pantier, Raphaël; Chhatbar, Kashyap; Quante, Timo; Skourti-Stathaki, Konstantina; Cholewa-Waclaw, Justyna; Alston, Grace; Alexander-Howden, Beatrice; Lee, Heng Yang; Cook, Atlanta G; Spruijt, Cornelia G; Vermeulen, Michiel; Selfridge, Jim; Bird, Adrian.

Mol Cell ; 81(4): 845-858.e8, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33406384

2.

Neuronal non-CG methylation is an essential target for MeCP2 function.

Tillotson, Rebekah; Cholewa-Waclaw, Justyna; Chhatbar, Kashyap; Connelly, John C; Kirschner, Sophie A; Webb, Shaun; Koerner, Martha V; Selfridge, Jim; Kelly, David A; De Sousa, Dina; Brown, Kyla; Lyst, Matthew J; Kriaucionis, Skirmantas; Bird, Adrian.

Mol Cell ; 81(6): 1260-1275.e12, 2021 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-33561390

3.

Do short, frequent DNA sequence motifs mould the epigenome?

Quante, Timo; Bird, Adrian.

Nat Rev Mol Cell Biol ; 17(4): 257-62, 2016 04.

Artigo em Inglês | MEDLINE | ID: mdl-26837845

4.

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes.

Skourti-Stathaki, Konstantina; Torlai Triglia, Elena; Warburton, Marie; Voigt, Philipp; Bird, Adrian; Pombo, Ana.

Mol Cell ; 73(5): 930-945.e4, 2019 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-30709709

5.

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.

Koerner, Martha V; FitzPatrick, Laura; Selfridge, Jim; Guy, Jacky; De Sousa, Dina; Tillotson, Rebekah; Kerr, Alastair; Sun, Zheng; Lazar, Mitchell A; Lyst, Matthew J; Bird, Adrian.

Genes Dev ; 32(23-24): 1514-1524, 2018 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-30463906

6.

The role of MeCP2 in the brain.

Guy, Jacky; Cheval, Hélène; Selfridge, Jim; Bird, Adrian.

Annu Rev Cell Dev Biol ; 27: 631-52, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21721946

7.

The Selfishness of Law-Abiding Genes.

Bird, Adrian.

Trends Genet ; 36(1): 8-13, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31662191

8.

Genome biology: not drowning but waving.

Bird, Adrian.

Cell ; 154(5): 951-952, 2013 Aug 29.

Artigo em Inglês | MEDLINE | ID: mdl-23993086

9.

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.

Tillotson, Rebekah; Selfridge, Jim; Koerner, Martha V; Gadalla, Kamal K E; Guy, Jacky; De Sousa, Dina; Hector, Ralph D; Cobb, Stuart R; Bird, Adrian.

Nature ; 550(7676): 398-401, 2017 10 19.

Artigo em Inglês | MEDLINE | ID: mdl-29019980

10.

Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing.

Chhatbar, Kashyap; Cholewa-Waclaw, Justyna; Shah, Ruth; Bird, Adrian; Sanguinetti, Guido.

PLoS Genet ; 16(10): e1009087, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-33048927

11.

Genetic therapies for neurological disorders.

FitzPatrick, Laura; Bird, Adrian.

Hum Genet ; 141(5): 1085-1091, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-34807307

12.

Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo.

Connelly, John C; Cholewa-Waclaw, Justyna; Webb, Shaun; Steccanella, Verdiana; Waclaw, Bartlomiej; Bird, Adrian.

Nucleic Acids Res ; 48(7): 3542-3552, 2020 04 17.

Artigo em Inglês | MEDLINE | ID: mdl-32064528

13.

Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.

Cholewa-Waclaw, Justyna; Shah, Ruth; Webb, Shaun; Chhatbar, Kashyap; Ramsahoye, Bernard; Pusch, Oliver; Yu, Miao; Greulich, Philip; Waclaw, Bartlomiej; Bird, Adrian P.

Proc Natl Acad Sci U S A ; 116(30): 14995-15000, 2019 07 23.

Artigo em Inglês | MEDLINE | ID: mdl-31289233

14.

Rett syndrome: a complex disorder with simple roots.

Lyst, Matthew J; Bird, Adrian.

Nat Rev Genet ; 16(5): 261-75, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25732612

15.

A mutation-led search for novel functional domains in MeCP2.

Guy, Jacky; Alexander-Howden, Beatrice; FitzPatrick, Laura; DeSousa, Dina; Koerner, Martha V; Selfridge, Jim; Bird, Adrian.

Hum Mol Genet ; 27(14): 2531-2545, 2018 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-29718204

16.

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

Kruusvee, Valdeko; Lyst, Matthew J; Taylor, Ceitidh; Tarnauskaite, Zygimante; Bird, Adrian P; Cook, Atlanta G.

Proc Natl Acad Sci U S A ; 114(16): E3243-E3250, 2017 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-28348241

17.

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.

Lagger, Sabine; Connelly, John C; Schweikert, Gabriele; Webb, Shaun; Selfridge, Jim; Ramsahoye, Bernard H; Yu, Miao; He, Chuan; Sanguinetti, Guido; Sowers, Lawrence C; Walkinshaw, Malcolm D; Bird, Adrian.

PLoS Genet ; 13(5): e1006793, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28498846

18.

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.

Clouaire, Thomas; Webb, Shaun; Skene, Pete; Illingworth, Robert; Kerr, Alastair; Andrews, Robert; Lee, Jeong-Heon; Skalnik, David; Bird, Adrian.

Genes Dev ; 26(15): 1714-28, 2012 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-22855832

19.

Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.

May, Stephanie; Owen, Heather; Phesse, Toby J; Greenow, Kirsty R; Jones, Gareth-Rhys; Blackwood, Adam; Cook, Peter C; Towers, Christopher; Gallimore, Awen M; Williams, Geraint T; Stürzl, Michael; Britzen-Laurent, Nathalie; Sansom, Owen J; MacDonald, Andrew S; Bird, Adrian P; Clarke, Alan R; Parry, Lee.

J Pathol ; 245(3): 270-282, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29603746

20.

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.

Ebert, Daniel H; Gabel, Harrison W; Robinson, Nathaniel D; Kastan, Nathaniel R; Hu, Linda S; Cohen, Sonia; Navarro, Adrija J; Lyst, Matthew J; Ekiert, Robert; Bird, Adrian P; Greenberg, Michael E.

Nature ; 499(7458): 341-5, 2013 Jul 18.

Artigo em Inglês | MEDLINE | ID: mdl-23770587

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