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Nat Prod Res ; 34(22): 3257-3261, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30760045

RESUMO

Many studies demonstrated that Algerian propolis possess a large spectrum of biological activity. However, few studies regarding its chemical composition are available on literature. We aimed in the present study to investigate the chemical composition of Algerian propolis. In addition, the antioxidants and anticholinesterase activities of propolis extracts are also reported. Chemical investigation of Algerian propolis allowed the isolation of 8 compounds. Their structures were identified on the basis of spectral data and comparison with literature. The isolated compounds are considered as markers of poplar and Citrus spp suggesting the use of both species as plant source of the tested propolis. The ethyl acetate extract of the tested propolis demonstrated the highest antioxidant activity. Among the tested extracts, only the petroleum ether and chloroform extracts exhibited an AChE inhibitory activity.


Assuntos
Antioxidantes/farmacologia , Inibidores da Colinesterase/farmacologia , Própole/química , Argélia , Antioxidantes/química , Compostos de Bifenilo/química , Clorofórmio/química , Inibidores da Colinesterase/química , Avaliação Pré-Clínica de Medicamentos , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Picratos/química , Extratos Vegetais/química , Solventes/química
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