Detalhe da pesquisa
1.
Genetics of Diffuse Idiopathic Skeletal Hyperostosis and Ossification of the Spinal Ligaments.
Curr Osteoporos Rep
; 21(5): 552-566, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37530996
2.
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
Nature
; 518(7537): 107-10, 2015 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409146
3.
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Nature
; 510(7506): 542-6, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24847880
4.
Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
J Biol Chem
; 289(6): 3294-306, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338010
5.
NPP4 is a procoagulant enzyme on the surface of vascular endothelium.
Blood
; 120(22): 4432-40, 2012 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22995898
6.
ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency.
Annu Rev Pathol
; 19: 507-540, 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37871131
7.
Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome.
Elife
; 122023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36930696
8.
Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
J Biol Chem
; 286(34): 30130-41, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21719699
9.
Strategies for Glycoengineering Therapeutic Proteins.
Front Chem
; 10: 863118, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35494652
10.
Direct targeting of amplified gene loci for proapoptotic anticancer therapy.
Nat Biotechnol
; 40(3): 325-334, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34711990
11.
Musculoskeletal Comorbidities and Quality of Life in ENPP1-Deficient Adults and the Response of Enthesopathy to Enzyme Replacement Therapy in Murine Models.
J Bone Miner Res
; 37(3): 494-504, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882836
12.
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass.
J Bone Miner Res
; 37(9): 1733-1749, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773783
13.
Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI).
Orphanet J Rare Dis
; 17(1): 273, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35854274
14.
Identification of ENPP1 Haploinsufficiency in Patients With Diffuse Idiopathic Skeletal Hyperostosis and Early-Onset Osteoporosis.
J Bone Miner Res
; 37(6): 1125-1135, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35340077
15.
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.
J Clin Invest
; 132(2)2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34813507
16.
Genetic pathways disrupted by ENPP1 deficiency provide insight into mechanisms of osteoporosis, osteomalacia, and paradoxical mineralization.
Bone
; 142: 115656, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980560
17.
Improving the Pharmacodynamics and In Vivo Activity of ENPP1-Fc Through Protein and Glycosylation Engineering.
Clin Transl Sci
; 14(1): 362-372, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33064927
18.
Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice.
J Bone Miner Res
; 36(5): 942-955, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33465815
19.
Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR.
Biochemistry
; 49(22): 4620-34, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20420426
20.
Next generation miRNA inhibition using short anti-seed PNAs encapsulated in PLGA nanoparticles.
J Control Release
; 327: 406-419, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32835710