Detalhe da pesquisa
1.
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase.
J Biol Chem
; 298(2): 101531, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953855
2.
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis.
Amino Acids
; 55(2): 215-233, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454288
3.
Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress.
J Neurochem
; 159(4): 742-761, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216036
4.
The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1.
Methods
; 175: 10-23, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31726226
5.
Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism.
Chembiochem
; 19(1): 85-99, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29112789
6.
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens.
Eur J Med Chem
; 264: 115971, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38071795
7.
Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity.
Metabolites
; 13(2)2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36837770
8.
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy.
Biomaterials
; 289: 121735, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055815
9.
Evaluation of kinetic data: What the numbers tell us about PRMTs.
Biochim Biophys Acta Proteins Proteom
; 1867(3): 306-316, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30342239
10.
Familial posterior fossa arachnoid cyst.
Childs Nerv Syst
; 20(2): 100-3, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14556029