Detalhe da pesquisa
1.
Effect of Apigenin on Leishmania amazonensis Is Associated with Reactive Oxygen Species Production Followed by Mitochondrial Dysfunction.
J Nat Prod
; 78(4): 880-4, 2015 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25768915
2.
Synthesis and activity of novel tetrazole compounds and their pyrazole-4-carbonitrile precursors against Leishmania spp.
Bioorg Med Chem Lett
; 23(23): 6310-2, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24125880
3.
In vitro and in vivo effects of (-)-epigallocatechin 3-O-gallate on Leishmania amazonensis.
J Nat Prod
; 76(10): 1993-6, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24106750
4.
Reactive oxygen species production by quercetin causes the death of Leishmania amazonensis intracellular amastigotes.
J Nat Prod
; 76(8): 1505-8, 2013 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23876028
5.
In vitro evaluation of 4-phenyl-5-(4'-X-phenyl)-1,3,4-thiadiazolium-2-phenylaminide chlorides and 3[N-4'-X-phenyl]-1,2,3-oxadiazolium-5-olate derivatives on nitric oxide synthase and arginase activities of Leishmania amazonensis.
Exp Parasitol
; 135(1): 50-4, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23693031
6.
The histopathological and immunological pattern of CBA mice infected with Leishmania amazonensis after treatment with pyrazole carbohydrazide derivatives.
Exp Parasitol
; 133(2): 201-10, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23219949
7.
The in vivo activity of 1,3,4-thiadiazolium-2-aminide compounds in the treatment of cutaneous and visceral leishmaniasis.
J Antimicrob Chemother
; 67(1): 182-90, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21987238
8.
Mitochondrial damage contribute to epigallocatechin-3-gallate induced death in Leishmania amazonensis.
Exp Parasitol
; 132(2): 151-5, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22735546
9.
4-(1H-Pyrazol-1-yl) benzenesulfonamide derivatives: identifying new active antileishmanial structures for use against a neglected disease.
Molecules
; 17(11): 12961-73, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23117435
10.
Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives.
Bioorg Med Chem Lett
; 21(24): 7451-4, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055204
11.
Evaluation of thiosemicarbazones and semicarbazones as potential agents anti-Trypanosoma cruzi.
Exp Parasitol
; 129(4): 381-7, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21939658
12.
A review of antimalarial plants used in traditional medicine in communities in Portuguese-speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola.
Mem Inst Oswaldo Cruz
; 106 Suppl 1: 142-58, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21881769
13.
Antileishmanial activity of 1,3,4-thiadiazolium-2-aminide in mice infected with Leishmania amazonensis.
Antimicrob Agents Chemother
; 53(2): 839-42, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19015338
14.
A comparative study of mesoionic compounds in Leishmania sp. and toxicity evaluation.
Eur J Med Chem
; 42(7): 1039-43, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17367894
15.
Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents.
Eur J Med Chem
; 42(11-12): 1388-95, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17445951
16.
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N'-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides.
Eur J Med Chem
; 41(1): 80-7, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16300859
17.
Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action.
PLoS Negl Trop Dis
; 10(2): e0004442, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26862901
18.
Synthesis, and biological evaluation of new 1,3,4-thiadiazolium-2-phenylamine derivatives against Leishmania amazonensis promastigotes and amastigotes.
Eur J Med Chem
; 37(12): 979-84, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12660023
19.
The effect of (-)-epigallocatechin 3-O--gallate in vitro and in vivo in Leishmania braziliensis: involvement of reactive oxygen species as a mechanism of action.
PLoS Negl Trop Dis
; 8(8): e3093, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25144225
20.
Effectiveness of novel 5-(5-amino-1-aryl-1H-pyrazol-4-yl)-1H-tetrazole derivatives against promastigotes and amastigotes of Leishmania amazonensis.
Chem Biol Drug Des
; 83(3): 272-7, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24119090