Detalhe da pesquisa
1.
Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry.
Cell Commun Signal
; 22(1): 186, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509561
2.
Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.
Blood
; 137(15): 2070-2084, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512435
3.
Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms.
Int J Mol Sci
; 24(24)2023 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139386
4.
KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile.
Int J Mol Sci
; 24(6)2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982353
5.
Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms.
Ann Hematol
; 101(12): 2655-2663, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36269400
6.
Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells.
Ann Hematol
; 100(12): 2943-2956, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390367
7.
LCP1 triggers mTORC2/AKT activity and is pharmacologically targeted by enzastaurin in hypereosinophilia.
Mol Carcinog
; 59(1): 87-103, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691359
8.
Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Blood
; 132(1): 67-77, 2018 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29784639
9.
Transcriptional alteration of DNA repair genes in Philadelphia chromosome negative myeloproliferative neoplasms.
Ann Hematol
; 98(12): 2703-2709, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748924
10.
Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition.
Haematologica
; 108(4): 1179-1185, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36453102
11.
Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia.
Ann Hematol
; 101(11): 2533-2536, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36125543
12.
Intercellular trafficking of the nuclear oncoprotein DEK.
Proc Natl Acad Sci U S A
; 110(17): 6847-52, 2013 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23569252
13.
Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.
Cell Commun Signal
; 13: 10, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25885255
14.
Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms.
Sci Rep
; 14(1): 2810, 2024 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38308077
15.
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Stem Cell Reports
; 19(2): 224-238, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38278152
16.
Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms.
Cell Rep
; 43(1): 113608, 2024 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117649
17.
Myelofibrosis at diagnosis is associated with the failure of treatment-free remission in CML patients.
Front Pharmacol
; 14: 1212392, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37469867
18.
The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling.
Front Oncol
; 13: 1277453, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37941547
19.
Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.
J Biol Chem
; 286(7): 5494-505, 2011 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21127067
20.
Mast cells as a therapeutic target in myeloproliferative neoplasms.
Trends Mol Med
; 28(11): 902-905, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36064534