1.
Cell
; 185(6): 939-940, 2022 03 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35263624
RESUMO
Every cell in our body accumulates mutations throughout life, and sometimes an unfortunate combination of mutations drives the initiation of cancer. A new study infers extraordinarily detailed timelines of pre-cancerous evolution by sequencing single-cell genomes in patients with blood malignancies-finding that key mutations can arrive decades before diagnosis.