Detalhe da pesquisa
1.
Hyperglycemia induces vascular smooth muscle cell dedifferentiation by suppressing insulin receptor substrate-1-mediated p53/KLF4 complex stabilization.
J Biol Chem
; 294(7): 2407-2421, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30578299
2.
THYROID DYSFUNCTION, RECOVERY, AND PROGNOSIS IN MELANOMA PATIENTS TREATED WITH IMMUNE CHECKPOINT INHIBITORS: A RETROSPECTIVE REVIEW.
Endocr Pract
; 26(1): 36-42, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31461358
3.
IGFBP-2 stimulates calcium/calmodulin-dependent protein kinase kinase 2 activation leading to AMP-activated protein kinase induction which is required for osteoblast differentiation.
J Cell Physiol
; 234(12): 23232-23242, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155724
4.
Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation.
J Biol Chem
; 292(5): 2009-2020, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003360
5.
The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase ß (RPTPß).
J Biol Chem
; 290(18): 11578-90, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25787077
6.
Budesonide foam induces remission in patients with mild to moderate ulcerative proctitis and ulcerative proctosigmoiditis.
Gastroenterology
; 148(4): 740-750.e2, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25644096
7.
Hyperglycemia stimulates p62/PKCζ interaction, which mediates NF-κB activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscle.
FASEB J
; 29(12): 4772-82, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231202
8.
Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I.
J Biol Chem
; 288(22): 15641-53, 2013 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23612968
9.
Medical Costs Associated with High/Moderate/Low Likelihood of Adult Growth Hormone Deficiency: A Healthcare Claims Database Analysis.
Clinicoecon Outcomes Res
; 16: 133-147, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38476578
10.
IGF binding protein 3 exerts its ligand-independent action by antagonizing BMP in zebrafish embryos.
J Cell Sci
; 124(Pt 11): 1925-35, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21558420
11.
Excellence in the treatment of patients with pituitary tumors.
Pituitary
; 21(1): 107, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29124563
12.
A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation.
Proc Natl Acad Sci U S A
; 107(23): 10508-13, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20498072
13.
Interpreting growth hormone and IGF-I results using modern assays and reference ranges for the monitoring of treatment effectiveness in acromegaly.
Front Endocrinol (Lausanne)
; 14: 1266339, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38027199
14.
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.
J Biol Chem
; 286(16): 14670-80, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21372140
15.
Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database.
Int J Endocrinol
; 2022: 7853786, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35761982
16.
p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.
J Biol Chem
; 285(10): 6937-51, 2010 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20048152
17.
PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.
J Biol Chem
; 285(38): 29416-24, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20643654
18.
Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.
J Biol Chem
; 285(21): 15682-95, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20207740
19.
Consensus statement on the standardization and evaluation of growth hormone and insulin-like growth factor assays.
Clin Chem
; 57(4): 555-9, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21285256
20.
ACCURATE DIAGNOSIS OF GROWTH HORMONE DEFICIENCY IN ADULTS: THE ONGOING CHALLENGE.
Endocr Pract
; 22(12): 1462-1464, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27929680