Detalhe da pesquisa
1.
A requirement for p120-catenin in the metastasis of invasive ductal breast cancer.
J Cell Sci
; 134(6)2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097605
2.
Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer.
Breast Cancer Res
; 24(1): 51, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35850776
3.
mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
PLoS Genet
; 11(7): e1005291, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132202
4.
ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.
Breast Cancer Res
; 19(1): 105, 2017 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886748
5.
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Breast Cancer Res
; 19(1): 74, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666462
6.
Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer.
Mol Cell Proteomics
; 14(7): 1959-76, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25953087
7.
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.
Proc Natl Acad Sci U S A
; 110(35): 14372-7, 2013 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940356
8.
Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers.
Breast Cancer Res
; 17: 148, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26637440
9.
The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium.
Proc Natl Acad Sci U S A
; 109(1): 221-6, 2012 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22178756
10.
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.
Proc Natl Acad Sci U S A
; 108(12): 5021-6, 2011 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21385943
11.
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy.
Nat Commun
; 15(1): 1581, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383524
12.
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing.
Biomaterials
; 297: 122098, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031547
13.
Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy.
bioRxiv
; 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36824780
14.
Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis.
bioRxiv
; 2023 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333210
15.
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.
J Clin Invest
; 118(1): 64-78, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18079969
16.
MLL3 is a de novo cause of endocrine therapy resistance.
Cancer Med
; 10(21): 7692-7711, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34581028
17.
Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch.
JCI Insight
; 6(19)2021 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34622803
18.
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer.
J Clin Invest
; 131(4)2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33320840
19.
Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation.
BMC Dev Biol
; 10: 122, 2010 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21192804
20.
Repurposing of a Thromboxane Receptor Inhibitor Based on a Novel Role in Metastasis Identified by Phenome-Wide Association Study.
Mol Cancer Ther
; 19(12): 2454-2464, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33033174