Detalhe da pesquisa
1.
UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.
J Biol Chem
; 288(31): 22576-83, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754276
2.
Design of Dual EP2/EP4 Antagonists through Scaffold Merging of Selective Inhibitors.
ChemMedChem
; 19(2): e202300606, 2024 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37983645
3.
Identification of a new chemical class of antimalarials.
J Infect Dis
; 206(5): 735-43, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22732921
4.
Design and optimization of new piperidines as renin inhibitors.
Bioorg Med Chem Lett
; 20(21): 6286-90, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20843686
5.
Piperidine-based renin inhibitors: upper chain optimization.
Bioorg Med Chem Lett
; 20(21): 6291-6, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20843690
6.
A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment.
J Org Chem
; 74(15): 5458-70, 2009 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19534538
7.
New classes of potent and bioavailable human renin inhibitors.
Bioorg Med Chem Lett
; 19(23): 6762-5, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19853442
8.
Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies.
J Med Chem
; 60(23): 9769-9789, 2017 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29116786
9.
Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.
J Med Chem
; 59(23): 10661-10675, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933950
10.
Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.
ChemMedChem
; 11(18): 1995-2014, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471138
11.
FPR2/ALXR agonists and the resolution of inflammation.
J Med Chem
; 58(2): 537-59, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25365541
12.
Enantioselective Diels-Alder reactions with N-hydroxy-N-phenylacrylamide.
Org Lett
; 4(10): 1731-3, 2002 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12000285
13.
N-alkoxyacrylamides as substrates for enantioselective Diels-Alder reactions.
Org Lett
; 4(10): 1735-8, 2002 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12000286
14.
Chiral relay effect: 4-substituted 1,3-benzoxazol-2-(3H)-ones as achiral templates for enantioselective Diels-Alder reactions.
Org Lett
; 4(1): 39-42, 2002 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-11772085
15.
Total synthesis of the reputed structure of alcyonin and reassignment of its structure.
Org Lett
; 5(9): 1543-6, 2003 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12713319
16.
Correction to Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.
J Med Chem
; 60(5): 2163, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28234473
17.
Design and preparation of potent, nonpeptidic, bioavailable renin inhibitors.
J Med Chem
; 52(12): 3689-702, 2009 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19358611
18.
Inhibitors of Plasmepsin II-potential antimalarial agents.
Bioorg Med Chem Lett
; 16(24): 6194-9, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17000102
19.
A computational study of radical haloacetal cyclizations controlled by the acetal center.
Chemistry
; 9(7): 1578-84, 2003 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12658656
20.
Enantioselective total synthesis of briarellins E and F: the first total syntheses of briarellin diterpenes.
J Am Chem Soc
; 125(22): 6650-2, 2003 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12769572