Turning a lost reef ecosystem into a national restoration program.

Achieving a sustainable socioecological future now requires large-scale environmental repair across legislative borders. Yet, enabling large-scale conservation is complicated by policy-making processes that are disconnected from socioeconomic interests, multiple sources of knowledge, and differing applications of policy. We considered how a multidisciplinary approach to marine habitat restoration generated the scientific evidence base, community support, and funding needed to begin the restoration of a forgotten, functionally extinct shellfish reef ecosystem. The key actors came together as a multidisciplinary community of researchers, conservation practitioners, recreational fisher communities, and government bodies that collaborated across sectors to rediscover Australia's lost shellfish reefs and communicate the value of its restoration. Actions undertaken to build a case for large-scale marine restoration included synthesizing current knowledge on Australian shellfish reefs and their historical decline, using this history to tell a compelling story to spark public and political interest, integrating restoration into government policy, and rallying local support through community engagement. Clearly articulating the social, economic, and environmental business case for restoration led to state and national funding for reef restoration to meet diverse sustainability goals (e.g., enhanced biodiversity and fisheries productivity) and socioeconomic goals (e.g., job creation and recreational opportunities). A key lesson learned was the importance of aligning project goals with public and industry interests so that projects could address multiple political obligations. This process culminated in Australia's largest marine restoration initiative and shows that solutions for large-scale ecosystem repair can rapidly occur when socially valued science acts on political opportunities.

Transformación de un Ecosistema Arrecifal Perdido en un Programa Nacional de Restauración Resumen Actualmente se requiere una reparación ambiental a gran escala que atraviese fronteras legislativas para lograr un futuro socio-ecológico sustentable. Aun así, habilitar la conservación a gran escala es complicado debido a los procesos de elaboración de políticas que están desconectadas de los intereses socio-económicos, las múltiples fuentes de conocimiento y las diferentes aplicaciones de las políticas. Consideramos cómo una estrategia multidisciplinaria para la restauración de hábitats marinos generó una base de evidencia científica, apoyo comunitario y el financiamiento necesario para así iniciar la restauración de un ecosistema arrecifal de conchas funcionalmente extinto. Los actores clave formaron una comunidad multidisciplinaria de investigadores, practicantes de la conservación, comunidades de pescadores recreativos y órganos gubernamentales que colaboró con varios sectores para redescubrir los arrecifes perdidos de Australia y comunicó el valor de su restauración. Las acciones realizadas para armar el caso para la restauración marina a gran escala incluyeron la síntesis del conocimiento actual sobre los arrecifes de conchas en Australia y su declinación histórica, el uso de esta historia para contar una narración convincente que active el interés público y político, la integración de la restauración a la política gubernamental y la movilización del apoyo local por medio de la participación comunitaria. Claramente, la articulación del caso del negocio social, económico y ambiental para la restauración llevó al financiamiento estatal y nacional para la restauración arrecifal a cumplir diversos objetivos socio-económicos (p. ej.: creación de empleos, oportunidades recreativas) y de restauración (p. ej.: una productividad realzada de la biodiversidad y las pesquerías). Una lección clave que aprendimos fue lo importante que es alinear los objetivos del proyecto con los intereses públicos y de la industria, de tal manera que los proyectos aborden las múltiples obligaciones políticas. Este proceso culminó con la iniciativa de restauración marina más grande en Australia y demuestra que las soluciones para la reparación de los ecosistemas a gran escala pueden ocurrir rápidamente cuando la ciencia con valor social actúa sobre las oportunidades políticas.

IDENTIFICATION OF A NASOCONCHAL PARANASAL SINUS IN THE WHITE RHINOCEROS ( CERATOTHERIUM SIMUM).

African rhinoceros are poached for their horns using indiscriminate and aggressive methods. Rhinoceros that survive these attacks often have severe facial trauma, and treatment is limited by a lack of understanding and published information of the normal anatomy. This study was performed to investigate and describe the anatomy of the most commonly injured area of the head of the white rhinoceros ( Ceratotherium simum). Two white rhinoceros cadaver heads were imaged by computed tomography and grossly dissected. A combined dorsal conchal sinus and nasal sinus (named the nasoconchal sinus) was identified and confirmed to be readily exposed by horn removal. The nasoconchal sinus communicates via a relatively large opening with the middle nasal meatus of the nasal cavity. Awareness of the combined sinus space and its single communicating pathway will assist with accurate assessment and treatment of trauma to the dorsal facial region of the white rhinoceros.

Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder.

BACKGROUND: Depression has been recognized as a common feature of Parkinson's disease (PD), and is the most prevalent psychiatric disorder in PD patients. OBJECTIVE: The authors sought to determine whether cognitive-behavioral therapy (CBT) is effective in the treatment of depression within the context of PD (dPD). METHOD: The authors enrolled 8 depressed PD patients into an open treatment study of 12 weeks of individual CBT treatment. RESULTS: There was a significant linear decrease in mean Hamilton Rating Scale for Depression (17-item) scores over Weeks 0 to 12, and 57% of patients (4/7) met criteria for remission at endpoint. CONCLUSION: This uncontrolled study suggests that CBT may be effective in treating dPD and may be an alternative or adjunct to pharmacological treatment.

Autonomous adaptation to climate-driven change in marine biodiversity in a global marine hotspot.

While governments and natural resource managers grapple with how to respond to climatic changes, many marine-dependent individuals, organisations and user-groups in fast-changing regions of the world are already adjusting their behaviour to accommodate these. However, we have little information on the nature of these autonomous adaptations that are being initiated by resource user-groups. The east coast of Tasmania, Australia, is one of the world's fastest warming marine regions with extensive climate-driven changes in biodiversity already observed. We present and compare examples of autonomous adaptations from marine users of the region to provide insights into factors that may have constrained or facilitated the available range of autonomous adaptation options and discuss potential interactions with governmental planned adaptations. We aim to support effective adaptation by identifying the suite of changes that marine users are making largely without government or management intervention, i.e. autonomous adaptations, to better understand these and their potential interactions with formal adaptation strategies.

Australian shellfish ecosystems: Past distribution, current status and future direction.

We review the status of marine shellfish ecosystems formed primarily by bivalves in Australia, including: identifying ecosystem-forming species, assessing their historical and current extent, causes for decline and past and present management. Fourteen species of bivalves were identified as developing complex, three-dimensional reef or bed ecosystems in intertidal and subtidal areas across tropical, subtropical and temperate Australia. A dramatic decline in the extent and condition of Australia's two most common shellfish ecosystems, developed by Saccostrea glomerata and Ostrea angasi oysters, occurred during the mid-1800s to early 1900s in concurrence with extensive harvesting for food and lime production, ecosystem modification, disease outbreaks and a decline in water quality. Out of 118 historical locations containing O. angasi-developed ecosystems, only one location still contains the ecosystem whilst only six locations are known to still contain S. glomerata-developed ecosystems out of 60 historical locations. Ecosystems developed by the introduced oyster Crasostrea gigas are likely to be increasing in extent, whilst data on the remaining 11 ecosystem-forming species are limited, preventing a detailed assessment of their current ecosystem-forming status. Our analysis identifies that current knowledge on extent, physical characteristics, biodiversity and ecosystem services of Australian shellfish ecosystems is extremely limited. Despite the limited information on shellfish ecosystems, a number of restoration projects have recently been initiated across Australia and we propose a number of existing government policies and conservation mechanisms, if enacted, would readily serve to support the future conservation and recovery of Australia's shellfish ecosystems.

A database of chlorophyll a in Australian waters.

Chlorophyll a is the most commonly used indicator of phytoplankton biomass in the marine environment. It is relatively simple and cost effective to measure when compared to phytoplankton abundance and is thus routinely included in many surveys. Here we collate 173, 333 records of chlorophyll a collected since 1965 from Australian waters gathered from researchers on regular coastal monitoring surveys and ocean voyages into a single repository. This dataset includes the chlorophyll a values as measured from samples analysed using spectrophotometry, fluorometry and high performance liquid chromatography (HPLC). The Australian Chlorophyll a database is freely available through the Australian Ocean Data Network portal (https://portal.aodn.org.au/). These data can be used in isolation as an index of phytoplankton biomass or in combination with other data to provide insight into water quality, ecosystem state, and relationships with other trophic levels such as zooplankton or fish.

Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder. A replication of findings with the use of a double-blind, placebo-controlled trial of Hypericum perforatum versus fluoxetine.

BACKGROUND: Our objective was to assess for the relationship between timing of clinical improvement and resolution of depressive symptoms during the treatment of major depressive disorder (MDD). Thirty-nine MDD outpatients who responded following a 12-week, double-blind study comparing Hypericum perforatum, fluoxetine or placebo were included in the analysis. METHODS: Onset of clinical improvement was defined as a 25% decrease in 17-item Hamilton Depression Scale (HDRS-17) scores that was not followed by a subsequent worsening of symptoms. Controlling for baseline symptom severity, we then assessed for the relationship between timing of clinical improvement and depressive symptom severity at endpoint. RESULTS: Among responders, earlier clinical improvement predicted lower HDRS-17 scores at week 12 (p = 0013). This was also true of responders who received active treatment (n = 29, p = 0.0113) but not placebo responders (n = 10; p > 0.05). Finally, patients with an early onset of clinical improvement (occurring during the first 2 weeks) had lower week 12 HDRS-17 scores than patients with a late onset of clinical improvement (p = 0.0404). CONCLUSION: In the present work, earlier as well as early clinical improvement during treatment is predictive of greater symptom resolution at endpoint among responders. This was replicated among patients who received active treatment (either hypericum or fluoxetine) but not placebo.

Evaluation of short-term fallowing as a strategy for the management of recurring organic enrichment under salmon cages.

Rotation of cages within fish farm leases and the subsequent fallowing of areas of seabed is commonly used to allow recovery of infaunal communities following periods of organic enrichment. To investigate the effect of different background environmental conditions on recovery response, two Atlantic salmon (Salmo salar) fish farm sites in southeast Tasmania were sampled over two commercial fallowing cycles. Despite similar stocking levels and feed input there were significant differences in the way in which sediment at each farm responded to the cessation of fish stocking. Sediments at both farms showed some improvement in the community structure over a three month fallow period, but the community structure only recovered to that present before stocking not to that at the reference sites. The similarity of the impact sites to the reference sites increased from ca. 25% to 31% at one site and 11% to 27% at the other after fallowing. Rate and extent of recovery were affected by farm location, initial impact of the sediments, and length of fallow period. Initial recovery was faster at the more sheltered site than at the more exposed site, possibly reflecting differences in environmental resilience with the more sheltered location better able to assimilate organic inputs. Accordingly general fallowing management protocols may need to be adapted to reflect differences between sites. The findings of this study suggest that the recovery response of benthic communities can be predicted once baseline conditions are understood.

Investigation of postoperative allograft-associated infections in patients who underwent musculoskeletal allograft implantation.

BACKGROUND: The rate at which allografts are used in surgical procedures has doubled in the United States during the past decade. In 2002, one outpatient surgical center (SC-X) identified a cluster of surgical site infections (SSIs) after anterior cruciate ligament reconstructive surgery (ACLRS). Therefore, we conducted an investigation to determine the extent of the outbreak and to identify risk factors. METHODS: Our investigation included retrospective cohort and observational studies. A case patient was defined as any patient who acquired a SSI after undergoing ACLRS at SC-X between February 2000 and June 2002 (the study period). Data collected included demographic characteristics, clinical information, and graft details, such as processing method (i.e., aseptic or sterile). RESULTS: Of 331 patients who underwent ACLRS during the study period, 11 (3.3%) met the case definition. All infections occurred at the tibial fixation site of the graft and involved 8 different microorganisms; the median time to a positive culture result was 55 days after ACLRS. The infection rate for patients who received aseptically processed allografts was 4.4% (11 of 250 patients), compared with 0% (0 of 81) for patients who received autografts or sterile allografts (P=.07). Use of a supplementary staple for tibial fixation, compared with other fixation methods that did not involve such staples, increased the risk of infection 10-fold in univariate analysis (relative risk [RR], 10.0; 95% confidence interval [CI], 3.0-32.9) and 9-fold when controlling for tissue processing method (RR, 9.0; 95% CI, 2.8-28.8). CONCLUSIONS: The use of sterile allograft tissue appears to be associated with a significant reduction in the risk of postoperative infection, particularly in the presence of adjunctive fixation. Larger clinical studies are necessary to confirm this observation.

Assessment of long term change in sediment condition after organic enrichment: defining recovery.

Sediment condition at an Atlantic salmon (Salmo salar) culture site in S.E. Tasmania, Australia was evaluated to determine the rate and extent of recovery after removal of farmed fish. By local standards the cage sediment at the start of this survey was markedly degraded but comparison with results from impact studies in Scotland, Canada and Norway suggests that the sediments were considerably less impacted than in northern temperate areas. The impact at the cages diminished rapidly with both time and distance; after only 2 months conditions were markedly improved. The macrobenthos indicated a slower recovery than chemical measures, after 36 months the benthic faunal community structure under the cages still differed from reference conditions even though other sediment measures had recovered. This study highlighted two other key issues in relation to monitoring and management of sediment recovery. First, techniques used to determine impact may not be appropriate for evaluation of recovery. Second, establishment of local baseline standards is extremely important to ensure appropriate evaluation of both impact and recovery.