Detalhe da pesquisa
1.
PCSK9 is minimally associated with HDL but impairs the anti-atherosclerotic HDL effects on endothelial cell activation.
J Lipid Res
; 63(10): 100272, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067830
2.
Structure-function analysis of naturally occurring apolipoprotein A-I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk.
Cell Mol Life Sci
; 78(4): 1523-1544, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666307
3.
ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aß production independently of their cholesterol efflux capacity.
Biochem J
; 475(10): 1839-1859, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743204
4.
Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells.
Biochim Biophys Acta Biomembr
; 1859(10): 1967-1973, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28688796
5.
Influence of Isoforms and Carboxyl-Terminal Truncations on the Capacity of Apolipoprotein E To Associate with and Activate Phospholipid Transfer Protein.
Biochemistry
; 54(38): 5856-66, 2015 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26337529
6.
Molecular basis for increased risk for late-onset Alzheimer disease due to the naturally occurring L28P mutation in apolipoprotein E4.
J Biol Chem
; 289(18): 12931-45, 2014 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24644280
7.
apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.
J Lipid Res
; 55(7): 1310-23, 2014 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24776540
8.
Corinthian Currants Promote the Expression of Paraoxonase-1 and Enhance the Antioxidant Status in Serum and Brain of 5xFAD Mouse Model of Alzheimer's Disease.
Biomolecules
; 14(4)2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672443
9.
Biochemical and genetic evidence for the presence of multiple phosphatidylinositol- and phosphatidylinositol 4,5-bisphosphate-specific phospholipases C in Tetrahymena.
Eukaryot Cell
; 10(3): 412-22, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21169416
10.
Temporal Pattern of Neuroinflammation Associated with a Low Glycemic Index Diet in the 5xFAD Mouse Model of Alzheimer's Disease.
Mol Neurobiol
; 59(12): 7303-7322, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36175825
11.
Mechanistic insight into the capacity of natural polar phenolic compounds to abolish Alzheimer's disease-associated pathogenic effects of apoE4 forms.
Free Radic Biol Med
; 171: 284-301, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019932
12.
An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42.
J Neurochem
; 115(4): 873-84, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20412390
13.
Activation of both transforming growth factor-ß and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia.
Brain Commun
; 1(1): fcz028, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32954268
14.
Amyloid-peptide ß 42 Enhances the Oligomerization and Neurotoxicity of apoE4: The C-terminal Residues Leu279, Lys282 and Gln284 Modulate the Structural and Functional Properties of apoE4.
Neuroscience
; 394: 144-155, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30367942
15.
Study of the Involvement of Phosphatidic Acid Formation in the Expression of Wound-Responsive Genes in Cotton.
Lipids
; 53(6): 589-599, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30198579
16.
The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.
Sci Rep
; 6: 30654, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27476701