Detalhe da pesquisa
1.
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.
Cell
; 175(7): 1958-1971.e15, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30449619
2.
RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
Nature
; 609(7925): 174-182, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002574
3.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.
PLoS Pathog
; 19(8): e1011614, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37651466
4.
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.
Nature
; 512(7513): 198-202, 2014 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25079315
5.
In situ visualization of telomere elongation patterns in human cells.
Nucleic Acids Res
; 41(18): e176, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23963699
6.
De novo design of drug-binding proteins with predictable binding energy and specificity.
Science
; 384(6691): 106-112, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574125
7.
De novo design of drug-binding proteins with predictable binding energy and specificity.
bioRxiv
; 2023 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187746
8.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo.
bioRxiv
; 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37131711
9.
A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor.
Mol Cancer Ther
; 21(7): 1076-1089, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439318
10.
PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors.
Mol Cancer Ther
; 21(11): 1722-1728, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35999657
11.
Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2.
Cancer Res
; 82(21): 3950-3961, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36273492
12.
A protein interaction landscape of breast cancer.
Science
; 374(6563): eabf3066, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591612
13.
In Situ Visualization of Telomere Length, Telomere Elongation, and TERT Expression in Single Cells.
Curr Protoc Cell Biol
; 85(1): e97, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31763768
14.
Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.
J Med Chem
; 62(11): 5330-5357, 2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042381
15.
Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells.
PLoS One
; 13(12): e0206525, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30517099