Detalhe da pesquisa
1.
Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma.
Blood
; 124(8): 1259-65, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25016003
2.
The diaryl oxazole PC-046 is a tubulin-binding agent with experimental anti-tumor efficacy in hematologic cancers.
Invest New Drugs
; 31(6): 1616-25, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24037082
3.
Characterization of a membrane-active anti-tumor agent, UA8967.
Invest New Drugs
; 31(3): 576-86, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23179338
4.
UA62784, a novel inhibitor of centromere protein E kinesin-like protein.
Mol Cancer Ther
; 8(1): 36-44, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19139111
5.
Characterization of novel diaryl oxazole-based compounds as potential agents to treat pancreatic cancer.
J Pharmacol Exp Ther
; 331(2): 636-47, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19657049
6.
Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.
Bioorg Med Chem Lett
; 19(16): 4752-5, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19615898
7.
Imexon-based combination chemotherapy in A375 human melanoma and RPMI 8226 human myeloma cell lines.
Cancer Chemother Pharmacol
; 59(6): 749-57, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17333195
8.
alpha6 integrin cleavage: sensitizing human prostate cancer to ionizing radiation.
Int J Radiat Biol
; 83(11-12): 761-7, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18058365
9.
Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/bortezomib) cytotoxicity in myeloma cell lines.
Cancer Res
; 65(9): 3828-36, 2005 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15867381
10.
Glucose 6-phosphate dehydrogenase overexpression models glucose deprivation and sensitizes lymphoma cells to apoptosis.
Antioxid Redox Signal
; 8(7-8): 1315-27, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16910779
11.
Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization.
Peptides
; 27(4): 921-30, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16412534
12.
Correlates of imexon sensitivity in human multiple myeloma cell lines.
Leuk Lymphoma
; 47(1): 97-109, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16321833
13.
Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model.
Transl Oncol
; 9(3): 228-35, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27267841
14.
Cytotoxic lignans from Larrea tridentata.
Phytochemistry
; 66(7): 811-5, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15797607
15.
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
Clin Cancer Res
; 9(9): 3312-9, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12960117
16.
Induction of apoptosis and cell cycle arrest by imexon in human pancreatic cancer cell lines.
Int J Gastrointest Cancer
; 36(1): 15-28, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16227632
17.
Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells.
Mol Cancer Ther
; 1(3): 185-95, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12467213
18.
Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.
Cancer Biol Ther
; 16(1): 43-51, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25485960
19.
Chemical basis for the biological activity of imexon and related cyanoaziridines.
J Med Chem
; 47(1): 218-23, 2004 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14695835
20.
Pyrimidoquinazoline-based antitumor agents. Design of topoisomerase II to DNA cross-linkers with activity against protein kinases.
J Med Chem
; 45(25): 5543-55, 2002 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12459022