Detalhe da pesquisa
1.
Lipid droplets can promote drug accumulation and activation.
Nat Chem Biol
; 16(2): 206-213, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932720
2.
Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.
Proc Natl Acad Sci U S A
; 112(35): 10950-5, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269569
3.
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.
Proc Natl Acad Sci U S A
; 110(39): 15602-7, 2013 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019500
4.
Tumor targeting, trifunctional dendritic wedge.
Bioconjug Chem
; 26(1): 78-89, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25350602
5.
Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.
J Am Chem Soc
; 135(11): 4537-49, 2013 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23448368
6.
Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Nat Commun
; 12(1): 7171, 2021 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887403
7.
Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix.
J Am Chem Soc
; 132(3): 941-3, 2010 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20041650
8.
Direct organocatalytic coupling of carboxylated piperazine-2,5-diones with indoles through conjugate addition of carbon nucleophiles to indolenine intermediates.
Tetrahedron Lett
; 51(4): 609-612, 2010 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161551
9.
R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.
Elife
; 92020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32432544
10.
Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine.
J Am Chem Soc
; 131(50): 18078-88, 2009 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20000859
11.
Efficient Organocatalytic alpha-Sulfenylation of Substituted Piperazine-2,5-diones.
Tetrahedron Lett
; 50(30): 4310-4313, 2009 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161311
12.
Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1.
Cancer Res
; 76(19): 5810-5821, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503929
13.
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.
Elife
; 52016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27996937
14.
Enantioselective organocatalytic alpha-sulfenylation of substituted diketopiperazines.
Tetrahedron Asymmetry
; 20(23): 2742-2750, 2009 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161615