Detalhe da pesquisa
1.
Structure-Activity Relationships and Discovery of (S)-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6H-pyrido[1,2-h][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer.
J Med Chem
; 67(2): 1421-1446, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190324
2.
Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2.
ACS Infect Dis
; 10(5): 1780-1792, 2024 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38651692
3.
Depletion of autoreactive plasma cells and treatment of lupus nephritis in mice using CEP-33779, a novel, orally active, selective inhibitor of JAK2.
J Immunol
; 187(7): 3840-53, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880982
4.
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes.
ACS Chem Neurosci
; 13(6): 751-765, 2022 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245037
5.
Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models.
Bioorg Med Chem Lett
; 21(1): 463-6, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074994
6.
A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779.
J Med Chem
; 55(11): 5243-54, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22594690
7.
Oxygen distributions in tissue measured by phosphorescence quenching.
Adv Exp Med Biol
; 510: 181-5, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12580425
8.
Measurement of tumor oxygenation using new frequency domain phosphorometers.
Comp Biochem Physiol A Mol Integr Physiol
; 132(1): 153-9, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12062204