Detalhe da pesquisa
1.
Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Proc Natl Acad Sci U S A
; 120(32): e2217800120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498871
2.
A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain.
Proc Natl Acad Sci U S A
; 120(47): e2305215120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972067
3.
C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment.
J Am Chem Soc
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843262
4.
The ubiquitin E3 ligase Parkin regulates neuronal CaV1.3 channel functional expression.
J Neurophysiol
; 128(6): 1555-1564, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350063
5.
The role of voltage-gated calcium channels in the pathogenesis of Parkinson's disease.
Int J Neurosci
; : 1-10, 2022 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993158
6.
Regulation of the Ca2+ channel α2δ-1 subunit expression by epidermal growth factor via the ERK/ELK-1 signaling pathway.
Am J Physiol Endocrinol Metab
; 319(1): E232-E244, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32369417
7.
Uncoupling the CRMP2-Ca V 2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model.
bioRxiv
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38895294
8.
Regulating neuronal excitability: The role of S-palmitoylation in NaV1.7 activity and voltage sensitivity.
PNAS Nexus
; 3(6): pgae222, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38894876
9.
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
Pain
; 165(4): 866-883, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37862053
10.
Intranasal CRMP2-Ubc9 inhibitor regulates Na V 1.7 to alleviate trigeminal neuropathic pain.
Pain
; 165(3): 573-588, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751532
11.
Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Neurobiol Pain
; 13: 100116, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36687466
12.
Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain.
Pain
; 164(7): 1473-1488, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36729125
13.
Intranasal CRMP2-Ubc9 Inhibitor Regulates Na V 1.7 to Alleviate Trigeminal Neuropathic Pain.
bioRxiv
; 2023 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502910
14.
Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors.
Pain
; 164(12): 2696-2710, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37366599
15.
The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Br J Pharmacol
; 180(9): 1267-1285, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245395
16.
Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons.
Neurobiol Pain
; 12: 100109, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36531612
17.
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+ Channels and Pain.
ACS Chem Neurosci
; 13(13): 2035-2047, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671441
18.
L5-6 Spinal Nerve Ligation-induced Neuropathy Changes the Location and Function of Ca2+ Channels and Cdk5 and Affects the Compound Action Potential in Adjacent Intact L4 Afferent Fibers.
Neuroscience
; 471: 20-31, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303780
19.
Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry.
ACS Chem Neurosci
; 12(8): 1299-1312, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33787218
20.
Some Like It Hot: Dynamic Control of Cav2.2 Channels By Chili Peppers.
Function (Oxf)
; 4(1): zqac066, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36632472