Detalhe da pesquisa
1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell
; 184(24): 5886-5901.e22, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822784
2.
Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease.
Proc Natl Acad Sci U S A
; 118(50)2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34893539
3.
Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands.
J Biol Chem
; 298(5): 101932, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35427647
4.
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs.
Nat Chem Biol
; 16(3): 240-249, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32080630
5.
Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes.
Mol Pharmacol
; 93(6): 645-656, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29695609
6.
Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.
Elife
; 122023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085667
7.
Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease.
Neuronal Signal
; 6(1): NS20210004, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35571495
8.
Host tissue proteomics reveal insights into the molecular basis of Schistosoma haematobium-induced bladder pathology.
PLoS Negl Trop Dis
; 16(2): e0010176, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167594
9.
M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease.
Sci Signal
; 15(760): eabm3720, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36378750
10.
Investigating protein expression, modifications and interactions in the brain: Protocol for preparing rodent brain tissue for mass spectrometry-based quantitative- and phospho-proteomics analysis.
Methods Cell Biol
; 166: 251-269, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34752336
11.
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity.
Cell Chem Biol
; 27(7): 806-816.e8, 2020 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32359426
12.
Variants of the EAAT2 Glutamate Transporter Gene Promoter Are Associated with Cerebral Palsy in Preterm Infants.
Mol Neurobiol
; 55(3): 2013-2024, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28271401