Detalhe da pesquisa
1.
Time-to-event estimands and loss to follow-up in oncology in light of the estimands guidance.
Pharm Stat
; 2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38553421
2.
Why estimands are needed to define treatment effects in clinical trials.
BMC Med
; 21(1): 276, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501156
3.
Defining estimands for efficacy assessment in single arm phase 1b or phase 2 clinical trials in oncology early development.
Pharm Stat
; 22(5): 921-937, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37403434
4.
First-in-human phase 1 study of budigalimab, an anti-PD-1 inhibitor, in patients with non-small cell lung cancer and head and neck squamous cell carcinoma.
Cancer Immunol Immunother
; 71(2): 417-431, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216247
5.
Disseminated Tumor Cells in the Bone Marrow of Patients with Operable Primary Breast Cancer: Prognostic Impact in Immunophenotypic Subgroups and Clinical Implication for Bisphosphonate Treatment.
Ann Surg Oncol
; 23(3): 757-66, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467455
6.
Inflammation-adapted liver stiffness values for improved fibrosis staging in patients with hepatitis C virus and alcoholic liver disease.
Liver Int
; 35(12): 2514-21, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26121926
7.
Methods for proper handling of overrunning and underrunning in phase II designs for oncology trials.
Stat Med
; 34(13): 2128-37, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25781860
8.
Performance of adaptive designs for single-armed phase II oncology trials.
J Biopharm Stat
; 25(3): 602-15, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-24905363
9.
Influence of insulin and glargine on outgrowth and number of circulating endothelial progenitor cells in type 2 diabetes patients: a partially double-blind, randomized, three-arm unicenter study.
Cardiovasc Diabetol
; 13: 137, 2014 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25300286
10.
Sensor-derived physical activity parameters can predict future falls in people with dementia.
Gerontology
; 60(6): 483-92, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171300
11.
Improvements in gait characteristics after intensive resistance and functional training in people with dementia: a randomised controlled trial.
BMC Geriatr
; 14: 73, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24924703
12.
Prognostic value of disseminated tumor cells in the bone marrow of patients with operable primary breast cancer: a long-term follow-up study.
Ann Surg Oncol
; 20(6): 1865-71, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23263703
13.
Optimal adaptive two-stage designs for phase II cancer clinical trials.
Biom J
; 55(6): 955-68, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23868324
14.
Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases (UICC stage IV): SYNCHRONOUS--a randomised controlled multicentre trial (ISRCTN30964555).
BMC Cancer
; 12: 142, 2012 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22480173
15.
Improving the flexibility and efficiency of phase II designs for oncology trials.
Biometrics
; 68(3): 886-92, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22150825
16.
Adaptive designs for single-arm phase II trials in oncology.
Pharm Stat
; 11(3): 241-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22411839
17.
Association of Baseline and Pharmacodynamic Biomarkers With Outcomes in Patients Treated With the PD-1 Inhibitor Budigalimab.
J Immunother
; 45(3): 167-179, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35034046
18.
Comments on 'Hypothesis testing for two-stage designs with over or under enrollment'.
Stat Med
; 35(9): 1558-9, 2016 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27042811
19.
Safety, pharmacokinetics, and efficacy of budigalimab with rovalpituzumab tesirine in patients with small cell lung cancer.
Cancer Treat Res Commun
; 28: 100405, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329846
20.
Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181).
Clin Transl Sci
; 14(1): 277-287, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32770720