Detalhe da pesquisa
1.
Optimizing the Design and Analysis of Future AKI Trials.
J Am Soc Nephrol
; 33(8): 1459-1470, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35831022
2.
Rationale, design, demographics and baseline characteristics of the randomized, controlled, Phase 2b SAPPHIRE study of verinurad plus allopurinol in patients with chronic kidney disease and hyperuricaemia.
Nephrol Dial Transplant
; 37(8): 1461-1471, 2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34383954
3.
In Vitro Assessment of the Drug-Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters.
J Pharmacol Exp Ther
; 378(2): 108-123, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34074714
4.
Effect of Intensive Urate Lowering With Combined Verinurad and Febuxostat on Albuminuria in Patients With Type 2 Diabetes: A Randomized Trial.
Am J Kidney Dis
; 77(4): 481-489, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33130235
5.
Novel insights into the disease transcriptome of human diabetic glomeruli and tubulointerstitium.
Nephrol Dial Transplant
; 35(12): 2059-2072, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853351
6.
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator.
Br J Clin Pharmacol
; 84(7): 1486-1493, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29468715
7.
In Reply to 'Verinurad/Febuxostat and Nephrotoxicity'.
Am J Kidney Dis
; 78(3): 468-469, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34126126
8.
Tralokinumab for moderate-to-severe UC: a randomised, double-blind, placebo-controlled, phase IIa study.
Gut
; 64(2): 243-9, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25304132
9.
A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma.
Invest New Drugs
; 32(1): 178-87, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24242861
10.
Pharmacokinetics, pharmacodynamics, and safety of verinurad with and without allopurinol in healthy Asian, Chinese, and non-Asian participants.
Pharmacol Res Perspect
; 10(3): e00929, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35593744
11.
Dapagliflozin Added to Verinurad Plus Febuxostat Further Reduces Serum Uric Acid in Hyperuricemia: The QUARTZ Study.
J Clin Endocrinol Metab
; 106(5): e2347-e2356, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33075806
12.
MicroRNA-31 Targets Thymic Stromal Lymphopoietin in Mucosal Infiltrated CD4+ T Cells: A Role in Achieving Mucosal Healing in Ulcerative Colitis?
Inflamm Bowel Dis
; 24(11): 2377-2385, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29889228
13.
Differences in human papillomavirus type may influence clinical outcome in early stage cervical cancer.
Anticancer Res
; 26(2A): 829-32, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16619476
14.
Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.
Oncogene
; 23(44): 7441-7, 2004 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15318175
15.
Validation of the IntelliCap® system as a tool to evaluate extended release profiles in human GI tract using metoprolol as model drug.
J Control Release
; 217: 300-7, 2015 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385166
16.
A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma.
Clin Cancer Res
; 17(7): 1998-2005, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21447719
17.
Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer.
Clin Cancer Res
; 17(21): 6822-30, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21878535
18.
Sorafenib inhibits tumor growth and vascularization of rhabdomyosarcoma cells by blocking IGF-1R-mediated signaling.
Onco Targets Ther
; 1: 67-78, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21127754
19.
Single cell analysis of G1 check points-the relationship between the restriction point and phosphorylation of pRb.
Exp Cell Res
; 305(2): 383-91, 2005 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15817163
20.
Sequential immunofluorescence staining and image analysis for detection of large numbers of antigens in individual cell nuclei.
Cytometry
; 47(1): 32-41, 2002 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11774347