Detalhe da pesquisa
1.
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Nature
; 581(7806): 71-76, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376954
2.
Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.
Ann Neurol
; 93(6): 1158-1172, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843330
3.
Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression.
Brain
; 146(7): 2944-2956, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36542469
4.
Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease.
Brain
; 146(7): 2928-2943, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36625756
5.
Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.
Ann Neurol
; 92(5): 729-744, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151869
6.
Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-ß monoclonal antibodies in dominantly inherited Alzheimer's disease.
Eur J Nucl Med Mol Imaging
; 50(9): 2669-2682, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017737
7.
Unsupervised high-frequency smartphone-based cognitive assessments are reliable, valid, and feasible in older adults at risk for Alzheimer's disease.
J Int Neuropsychol Soc
; 29(5): 459-471, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36062528
8.
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes.
Brain
; 145(12): 4506-4518, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867858
9.
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment.
Brain
; 145(6): 1924-1938, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919634
10.
Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan.
Brain
; 145(12): 4459-4473, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35925685
11.
Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.
Brain
; 145(10): 3594-3607, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580594
12.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Nature
; 549(7673): 523-527, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28959956
13.
Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease.
Alzheimers Dement
; 19(7): 2923-2932, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640138
14.
Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study.
Alzheimers Dement
; 19(11): 4999-5009, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37087693
15.
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aß-PET, neurodegeneration, and cognition.
Alzheimers Dement
; 19(7): 2790-2804, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36576155
16.
Biomarker clustering in autosomal dominant Alzheimer's disease.
Alzheimers Dement
; 19(1): 274-284, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35362200
17.
Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.
Alzheimers Dement
; 19 Suppl 9: S115-S125, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491668
18.
Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease.
Neuroimage
; 256: 119228, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452806
19.
Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage.
Neurobiol Dis
; 166: 105662, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167933
20.
CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease.
Neurobiol Dis
; 168: 105714, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35358703