Detalhe da pesquisa
1.
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis.
J Enzyme Inhib Med Chem
; 37(1): 781-791, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35193444
2.
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles.
Bioorg Med Chem Lett
; 37: 127843, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33556576
3.
Efficacy of Novel Pyrazolone Phosphodiesterase Inhibitors in Experimental Mouse Models of Trypanosoma cruzi.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32601163
4.
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies.
Parasitology
; 147(11): 1216-1228, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32530391
5.
Imidazole Derivatives as Promising Agents for the Treatment of Chagas Disease.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670432
6.
Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi.
Parasitol Res
; 117(11): 3367-3380, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232605
7.
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.
Parasitology
; 143(11): 1469-78, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312370
8.
Novel solid dispersions of benznidazole: preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system.
Exp Parasitol
; 149: 84-91, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583295
9.
Trypanocidal Activity of Long Chain Diamines and Aminoalcohols.
Molecules
; 20(6): 11554-68, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111182
10.
In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents.
Bioorg Med Chem Lett
; 24(4): 1209-13, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24461296
11.
Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles.
Parasitol Res
; 113(3): 1049-56, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24435615
12.
Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing ß-galactosidase.
Bioorg Med Chem Lett
; 23(17): 4851-6, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23899616
13.
Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.
J Med Chem
; 66(19): 13452-13480, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729094
14.
5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents.
Acta Trop
; 234: 106607, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907502
15.
Trichomonas vaginalis: diagnóstico de una infección de transmisión sexual olvidada / Trichomonas vaginalis: diagnosis of a forgotten sexually transmitted infection
An. R. Acad. Nac. Farm. (Internet)
; 89(2): 135-147, Abril - Junio 2023. ilus, graf, tab
Artigo
em Espanhol
| IBECS (Espanha) | ID: ibc-223520
16.
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.
ChemMedChem
; 13(12): 1246-1259, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29624912
17.
New Imidazole-Based Compounds Active Against Trypanosoma cruzi.
Comb Chem High Throughput Screen
; 20(1): 20-24, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28071587
18.
Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties.
Eur J Med Chem
; 136: 223-234, 2017 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28499168
19.
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.
Eur J Med Chem
; 115: 295-310, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017556
20.
Development of novel benznidazole formulations: physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease.
Int J Pharm
; 472(1-2): 110-7, 2014 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24928135