Detalhe da pesquisa
1.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
2.
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity.
Mol Ther
; 30(9): 2968-2983, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450821
3.
Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.
J Infect Dis
; 224(5): 749-753, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244768
4.
ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model.
Biochem Biophys Res Commun
; 555: 134-139, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33813272
5.
Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012754
6.
Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.
EBioMedicine
; 100: 104960, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232633
7.
Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model.
Microorganisms
; 10(3)2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35336208
8.
The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters.
Antiviral Res
; 198: 105253, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35066015
9.
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.
Nat Commun
; 13(1): 719, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169114
10.
Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamsters.
Nat Commun
; 13(1): 6644, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36333374
11.
Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Nat Microbiol
; 7(9): 1376-1389, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35879526
12.
HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.
Antiviral Res
; 202: 105311, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390430
13.
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.
Microorganisms
; 10(8)2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36014057
14.
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters.
EBioMedicine
; 68: 103403, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049240
15.
The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model.
EBioMedicine
; 72: 103595, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571361
16.
A highly potent antibody effective against SARS-CoV-2 variants of concern.
Cell Rep
; 37(2): 109814, 2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599871
17.
An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Sci Transl Med
; 13(621): eabi7826, 2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34609205
18.
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.
mBio
; 9(5)2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30301850
19.
Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhibitors.
Drug Discov Today
; 22(3): 526-533, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27666194