Detalhe da pesquisa
1.
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
Cell
; 184(15): 3949-3961.e11, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161776
2.
VSIG4 interaction with heparan sulfates inhibits VSIG4-complement binding.
Glycobiology
; 33(7): 591-604, 2023 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341346
3.
NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity.
Hum Mol Genet
; 29(21): 3516-3531, 2021 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105479
4.
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc Natl Acad Sci U S A
; 117(1): 292-299, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879340
5.
Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J Allergy Clin Immunol
; 149(1): 200-211, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34126155
6.
Structural insights into mis-regulation of protein kinase A in human tumors.
Proc Natl Acad Sci U S A
; 112(5): 1374-9, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605907
7.
Structural Analysis of Cancer-relevant TCR-CD3 and Peptide-MHC Complexes by CryoEM.
Microsc Microanal
; 29(29 Suppl 1): 892, 2023 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37613478
8.
Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J Biol Chem
; 290(11): 6715-30, 2015 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25572397
9.
Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface.
Proteins
; 84(9): 1246-56, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27191504
10.
Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins
; 83(12): 2124-36, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26033498
11.
Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv
; 9(11): eade4395, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36930708
12.
Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun
; 14(1): 2401, 2023 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100770
13.
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell
; 5(4): 317-28, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15093539
14.
A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade.
Mol Cancer Ther
; 20(10): 1966-1976, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34315762
15.
Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres.
Bioorg Med Chem Lett
; 20(7): 2229-33, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20189383
16.
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models.
Clin Cancer Res
; 26(6): 1408-1419, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848185
17.
Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
Biochem J
; 385(Pt 1): 11-20, 2005 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15485396
18.
Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.
J Mol Biol
; 426(17): 3057-68, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24907552
19.
Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.
PLoS One
; 8(5): e63369, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23704901
20.
Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J Med Chem
; 55(22): 10282-6, 2012 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035744