Detalhe da pesquisa
1.
In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.
J Neurosci
; 35(47): 15716-30, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26609163
2.
Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline.
J Neurosci
; 35(38): 13029-42, 2015 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26400934
3.
Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons.
Eur J Neurosci
; 41(8): 1025-35, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25816842
4.
MER5101, a novel Aß1-15:DT conjugate vaccine, generates a robust anti-Aß antibody response and attenuates Aß pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice.
J Neurosci
; 33(16): 7027-37, 2013 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23595760
5.
Pyroglutamate-3 amyloid-ß deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Am J Pathol
; 183(2): 369-81, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23747948
6.
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aß by microglia.
Glia
; 60(6): 993-1003, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22438044
7.
Passive immunization against pyroglutamate-3 amyloid-ß reduces plaque burden in Alzheimer-like transgenic mice: a pilot study.
Neurodegener Dis
; 10(1-4): 265-70, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343072
8.
Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension.
Sci Rep
; 12(1): 7803, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35551212
9.
Effector function of anti-pyroglutamate-3 Aß antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice.
Alzheimers Res Ther
; 12(1): 12, 2020 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31931873
10.
Space-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice.
Sci Rep
; 9(1): 12118, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31431669
11.
Microglia: Architects of the Developing Nervous System.
Trends Cell Biol
; 26(8): 587-597, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27004698
12.
Immunotherapy targeting pyroglutamate-3 Aß: prospects and challenges.
Mol Neurodegener
; 11(1): 48, 2016 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27363697
13.
An anti-pyroglutamate-3 Aß vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice.
Neurobiol Aging
; 36(12): 3187-3199, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453001
14.
Deposition of phosphorylated amyloid-ß in brains of aged nonhuman primates and canines.
Brain Pathol
; 28(3): 427-430, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29740941
15.
Dietary supplementation with S-adenosyl methionine delayed amyloid-ß and tau pathology in 3xTg-AD mice.
J Alzheimers Dis
; 28(2): 423-31, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22045486
16.
Galactic cosmic radiation leads to cognitive impairment and increased aß plaque accumulation in a mouse model of Alzheimer's disease.
PLoS One
; 7(12): e53275, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300905