Detalhe da pesquisa
1.
Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.
Anal Chem
; 92(16): 11018-11028, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658454
2.
Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists.
Bioorg Med Chem Lett
; 28(8): 1313-1319, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29548571
3.
Identification of an aminothiazole series of RORß modulators.
Bioorg Med Chem Lett
; 28(7): 1178-1181, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534930
4.
Identification of potent RORß modulators: Scaffold variation.
Bioorg Med Chem Lett
; 28(19): 3210-3215, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143422
5.
SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.
J Proteome Res
; 14(11): 4571-80, 2015 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26398198
6.
High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2.
SLAS Discov
; 28(3): 95-101, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36646172
7.
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.
J Biol Chem
; 285(7): 5013-25, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19965867
8.
Molecular basis for the thiol sensitivity of insulin-degrading enzyme.
Proc Natl Acad Sci U S A
; 105(28): 9582-7, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18621727
9.
Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.
J Mol Biol
; 433(22): 167258, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547329
10.
The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.
Mol Pharmacol
; 77(2): 228-36, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19887649
11.
High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2.
SLAS Discov
; 25(10): 1152-1161, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33043784
12.
Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways.
ACS Chem Biol
; 14(5): 1051-1062, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30951276
13.
HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Elife
; 82019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31172947
14.
HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
Nat Commun
; 9(1): 5366, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30560918
15.
HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.
Nat Commun
; 8(1): 923, 2017 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29030554
16.
Synthetic RORγt Agonists Enhance Protective Immunity.
ACS Chem Biol
; 11(4): 1012-8, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26785144
17.
N-Arylsulfonyl Indolines as Retinoic Acid Receptor-Related Orphan Receptorâ γ (RORγ) Agonists.
ChemMedChem
; 11(23): 2607-2620, 2016 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27879053
18.
Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists.
ACS Med Chem Lett
; 6(9): 998-1003, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396687
19.
Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Elife
; 82019 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625909
20.
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife
; 3: e02057, 2014 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24771768