Detalhe da pesquisa
1.
6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor.
Bioorg Med Chem Lett
; 94: 129454, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591316
2.
Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.
Angew Chem Int Ed Engl
; 56(48): 15309-15313, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28960645
3.
Accessing Drug Metabolites via Transition-Metal Catalyzed C-H Oxidation: The Liver as Synthetic Inspiration.
Angew Chem Int Ed Engl
; 55(46): 14218-14238, 2016 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27723189
4.
Complementation of biotransformations with chemical C-H oxidation: copper-catalyzed oxidation of tertiary amines in complex pharmaceuticals.
J Am Chem Soc
; 135(33): 12346-52, 2013 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23875728
5.
The stereocontrolled total synthesis of spirastrellolide A methyl ester. Expedient construction of the key fragments.
Org Biomol Chem
; 10(30): 5861-72, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22504866
6.
Metal-Free-Visible Light C-H Alkylation of Heteroaromatics via Hypervalent Iodine-Promoted Decarboxylation.
Org Lett
; 20(11): 3229-3232, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29767991
7.
Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents.
J Med Chem
; 61(13): 5704-5718, 2018 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29878763
8.
Synthesis of two diastereomeric C1-C22 fragments of spirastrellolide A.
Chem Commun (Camb)
; (18): 1852-4, 2007 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17476409
9.
One-Pot Synthesis of α-Branched N-Acylamines via Titanium-Mediated Condensation of Amides, Aldehydes, and Organometallics.
Org Lett
; 19(5): 1064-1067, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199125
10.
Total synthesis of spirastrellolide A methyl ester--part 1: Synthesis of an advanced C17-C40 bis-spiroacetal subunit.
Angew Chem Int Ed Engl
; 47(16): 3016-20, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18307178
11.
Total synthesis of spirastrellolide A methyl ester--part 2: Subunit union and completion of the synthesis.
Angew Chem Int Ed Engl
; 47(16): 3021-5, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18307179
12.
Synthesis of sterically hindered enamides via a Ti-mediated condensation of amides with aldehydes and ketones.
Chem Commun (Camb)
; 48(53): 6735-7, 2012 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22643736