Detalhe da pesquisa
1.
A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant.
J Virol
; 96(13): e0068522, 2022 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674432
2.
Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies.
Int J Mol Sci
; 24(3)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768484
3.
Histamine H3 receptor antagonists with peptidomimetic (keto)piperazine structures to inhibit Aß oligomerisation.
Bioorg Med Chem
; 50: 116462, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34695709
4.
In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 22(12)2021 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34207233
5.
Oral Treatment with RD2RD2 Impedes Development of Motoric Phenotype and Delays Symptom Onset in SOD1G93A Transgenic Mice.
Int J Mol Sci
; 22(13)2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209129
6.
An orally available Cav2.2 calcium channel inhibitor for the treatment of neuropathic pain.
Br J Pharmacol
; 181(12): 1734-1756, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38157867
7.
Discovery of All-d-Peptide Inhibitors of SARS-CoV-2 3C-like Protease.
ACS Chem Biol
; 18(2): 315-330, 2023 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36647580
8.
The Importance of Epigallocatechin as a Scaffold for Drug Development against Flaviviruses.
Pharmaceutics
; 15(3)2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36986663
9.
Tau protein aggregation associated with SARS-CoV-2 main protease.
PLoS One
; 18(8): e0288138, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603556
10.
Evaluation of the 18F-labeled analog of the therapeutic all-D-enantiomeric peptide RD2 for amyloid ß imaging.
Eur J Pharm Sci
; 184: 106421, 2023 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889654
11.
Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold.
Pharmaceuticals (Basel)
; 15(5)2022 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35631367
12.
Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo.
Biomolecules
; 12(3)2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327661
13.
The Repurposed Drugs Suramin and Quinacrine Cooperatively Inhibit SARS-CoV-2 3CLpro In Vitro.
Viruses
; 13(5)2021 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34068686
14.
Oral absorption enhancement of the amyloid-ß oligomer eliminating compound RD2 by conjugation with folic acid.
Eur J Pharm Sci
; 156: 105581, 2021 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035662
15.
Toward the Mode of Action of the Clinical Stage All-d-Enantiomeric Peptide RD2 on Aß42 Aggregation.
ACS Chem Neurosci
; 10(12): 4800-4809, 2019 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31710458
16.
Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-ß oligomers.
Sci Rep
; 9(1): 5715, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30952881
17.
In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer's Disease.
J Alzheimers Dis
; 64(3): 859-873, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29966196