Detalhe da pesquisa
1.
Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.
Drug Metab Dispos
; 52(5): 355-367, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485280
2.
Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model.
Mol Pharm
; 21(5): 2284-2297, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38529622
3.
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.
Pharm Res
; 41(3): 557-566, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38302834
4.
Semisynthesis, Characterization, and Biological Evaluation of Fluorinated Analogues of the Spirobisnaphthalene, Diepoxin-η.
Tetrahedron Lett
; 1342024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328000
5.
Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.
Drug Metab Dispos
; 51(11): 1483-1489, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562957
6.
A Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross-Linked Cyclopeptides.
Angew Chem Int Ed Engl
; 62(7): e202218082, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36529706
7.
Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Phytother Res
; 35(6): 3286-3297, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587330
8.
The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids.
J Nat Prod
; 83(7): 2165-2177, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32597657
9.
Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production.
Planta Med
; 86(13-14): 988-996, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32219776
10.
Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder.
Planta Med
; 85(1): 32-40, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30153692
11.
Delitpyrones: α-Pyrone Derivatives from a Freshwater Delitschia sp.
Planta Med
; 85(1): 62-71, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30016827
12.
Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach.
J Nat Prod
; 80(6): 1883-1892, 2017 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28594169
13.
Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study.
J Nat Prod
; 80(5): 1457-1466, 2017 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453261
14.
Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides.
Drug Metab Dispos
; 43(11): 1734-43, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26316643
15.
Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris.
European J Org Chem
; 2015(1): 109-121, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25574154
16.
Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.
Drug Metab Dispos
; 42(10): 1675-83, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25008344
17.
Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum).
J Nat Prod
; 77(2): 193-9, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24456525
18.
A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.
Drug Metab Dispos
; 41(9): 1662-70, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801821
19.
HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case.
J Org Chem
; 78(7): 2827-39, 2013 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23461697
20.
Enhanced bioactivity of silybin B methylation products.
Bioorg Med Chem
; 21(3): 742-7, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23260576