Detalhe da pesquisa
1.
Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 1 Efficacy: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.
Anesth Analg
; 124(3): 821-830, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622720
2.
Translational Pharmacodynamics of Calcitonin Gene-Related Peptide Monoclonal Antibody LY2951742 in a Capsaicin-Induced Dermal Blood Flow Model.
J Pharmacol Exp Ther
; 354(3): 350-7, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26116630
3.
Advancing novel anesthetics: pharmacodynamic and pharmacokinetic studies of cyclopropyl-methoxycarbonyl metomidate in dogs.
Anesthesiology
; 121(6): 1203-16, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25170571
4.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the CGRP Binding Monoclonal Antibody LY2951742 (Galcanezumab) in Healthy Volunteers.
Front Pharmacol
; 8: 740, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089894
5.
Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled study.
Lancet Neurol
; 13(9): 885-92, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25127173
6.
A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas.
Clin Cancer Res
; 19(21): 6020-9, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24045182
7.
A phase 1 study of IPI-504 (retaspimycin hydrochloride) in patients with relapsed or relapsed and refractory multiple myeloma.
Leuk Lymphoma
; 52(12): 2308-15, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21851215
8.
Site of effect of LY2951742 for migraine prophylaxis--authors' reply.
Lancet Neurol
; 14(1): 32-3, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25496895
9.
Activity of IPI-504, a novel heat-shock protein 90 inhibitor, in patients with molecularly defined non-small-cell lung cancer.
J Clin Oncol
; 28(33): 4953-60, 2010 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940188
10.
Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells.
Blood
; 110(2): 678-85, 2007 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17395781
11.
Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
Proc Natl Acad Sci U S A
; 103(46): 17408-13, 2006 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17090671