Detalhe da pesquisa
1.
High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury.
Mol Ther
; 32(4): 952-968, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38327046
2.
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques.
Gene Ther
; 31(3-4): 128-143, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833563
3.
Intranasal gene therapy to prevent infection by SARS-CoV-2 variants.
PLoS Pathog
; 17(7): e1009544, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34265018
4.
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell
; 132(3): 397-409, 2008 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18267072
5.
Increasing the Specificity of AAV-Based Gene Editing through Self-Targeting and Short-Promoter Strategies.
Mol Ther
; 29(3): 1047-1056, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359790
6.
Muscle-directed AAV gene therapy rescues the maple syrup urine disease phenotype in a mouse model.
Mol Genet Metab
; 134(1-2): 139-146, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454844
7.
Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing.
BMC Genomics
; 21(1): 810, 2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33218308
8.
ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing.
BMC Genomics
; 21(1): 239, 2020 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183699
9.
Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.
Mol Genet Metab
; 125(3): 241-250, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30253962
10.
Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis.
Cancer Gene Ther
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38480976
11.
Prevalent and Disseminated Recombinant and Wild-Type Adeno-Associated Virus Integration in Macaques and Humans.
Hum Gene Ther
; 34(21-22): 1081-1094, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37930949
12.
Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model.
Mol Ther Methods Clin Dev
; 29: 32-39, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36936447
13.
Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration.
Nat Biotechnol
; 2023 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37932420
14.
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
Blood
; 116(15): 2656-64, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610817
15.
Erratum: Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors.
Mol Ther Methods Clin Dev
; 27: 450-451, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36419470
16.
Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors.
Mol Ther Methods Clin Dev
; 27: 272-280, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36320416
17.
Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A.
Hum Gene Ther
; 33(7-8): 421-431, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34652966
18.
Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases.
Hum Gene Ther
; 33(21-22): 1174-1186, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375122
19.
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.
Arterioscler Thromb Vasc Biol
; 30(4): 716-23, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20110569
20.
Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors.
Mol Ther
; 18(12): 2139-45, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20978477