Detalhe da pesquisa
1.
Replication stress links structural and numerical cancer chromosomal instability.
Nature
; 494(7438): 492-496, 2013 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23446422
2.
Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation.
Nucleic Acids Res
; 40(14): 6585-94, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505579
3.
UV stalled replication forks restart by re-priming in human fibroblasts.
Nucleic Acids Res
; 39(16): 7049-57, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21646340
4.
MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.
Cancer Res
; 80(17): 3530-3541, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32312836
5.
Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation.
Cell Cycle
; 17(5): 568-579, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976232
6.
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nat Commun
; 9(1): 3872, 2018 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30250201
7.
BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine.
Mol Cancer Ther
; 13(10): 2412-21, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25053826
8.
DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells.
DNA Repair (Amst)
; 11(12): 976-85, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23099010
9.
Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.
J Mol Biol
; 402(1): 70-82, 2010 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20643142
10.
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.
J Cell Biol
; 188(5): 629-38, 2010 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20194642