Detalhe da pesquisa
1.
Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells.
Bioorg Med Chem
; 40: 116187, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965840
2.
Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.
Bioorg Med Chem
; 29: 115853, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214035
3.
Pancreatic Lipase Inhibitory Cyclohexapeptides from the Marine Sponge-Derived Fungus Aspergillus sp. 151304.
J Nat Prod
; 83(7): 2287-2293, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662266
4.
Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2.
Bioorg Chem
; 105: 104367, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33080495
5.
Inhibition of pancreatic lipase by environmental xenoestrogens.
Ecotoxicol Environ Saf
; 192: 110305, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32070782
6.
Biflavones from Ginkgo biloba as inhibitors of human thrombin.
Bioorg Chem
; 92: 103199, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31446241
7.
Discovery of a Highly Divergent Coronavirus in the Asian House Shrew from China Illuminates the Origin of the Alphacoronaviruses.
J Virol
; 91(17)2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637760
8.
A new pre-column derivatization for valienamine and beta-valienamine using o-phthalaldehyde to determine the epimeric purity by HPLC and application of this method to monitor enzymatic catalyzed synthesis of beta-valienamine.
J Asian Nat Prod Res
; 19(4): 347-357, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28367638
9.
METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
Biochim Biophys Acta Mol Cell Res
; 1871(5): 119716, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547933
10.
Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug-Drug Interaction Studies.
J Med Chem
; 66(10): 6743-6755, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37145039
11.
Mettl3 synergistically regulates TGF-ß/SMAD2/3 to promote proliferation and metastasis of gastric cancer.
Am J Cancer Res
; 13(7): 3185-3202, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37560008
12.
IGF2BP2-modified UBE2D1 interacts with Smad2/3 to promote the progression of breast cancer.
Am J Cancer Res
; 13(7): 2948-2968, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37560007
13.
The efficiency and safety of alendronate versus teriparatide for treatment glucocorticoid-induced osteoporosis: A meta-analysis and systematic review of randomized controlled trials.
PLoS One
; 17(5): e0267706, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35639783
14.
Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay.
J Pharm Anal
; 12(4): 683-691, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36105167
15.
Five Chinese pediatric patients with leukemias possibly arising from immature natural killer cells: clinical features and courses.
Pediatr Hematol Oncol
; 28(3): 187-93, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21271777
16.
Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening.
Fitoterapia
; 152: 104909, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33894315
17.
Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2.
Front Pharmacol
; 12: 655659, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34084136
18.
Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms.
Int J Biol Macromol
; 187: 976-987, 2021 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333006
19.
Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors.
Eur J Med Chem
; 209: 112856, 2021 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007602
20.
Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations.
Eur J Drug Metab Pharmacokinet
; 46(1): 129-139, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33140264