Exploring the relationship between basketball rotation and competitive performance using substitution network analysis.

The aim of this exploratory study is (1) to determine the relationship between substitution network (Sub-N) parameters and teams' standings and (2) to find out the key individual performance indicators that differentiated substitution groups of players, and explore the association between players' percentages and team's standing within the obtained substitution groups. A total of 574,214 substitution events during the last 10 NBA seasons were analysed to construct Sub-N for each team observation. Three different player groups were obtained after clustering their playing time, clustering coefficient and vulnerability. Team's clustering coefficient, standard deviation of vulnerability and out-degree centrality of starters exhibited moderate to strong correlations with team's standing during playoffs (r = 0.54-0.76). The regression models showed that defensive win share (beta = 0.54-0.67), turnovers (-0.15 to -0.25) and assists (0.12-0.26) were predictive for all players' net ratings, and the role players who scored more points presented higher net ratings (0.34). Finally, players from top-playoff teams exhibited lower absolute value of vulnerabilities (r = 0.80). The findings demonstrate the feasibility of Sub-N for exploring the association between rotation and competitive performance, and provide quantitative reference for coaching staff to optimize substitution structures and rosters.

Phase-Controllable Cobalt Phosphides Induced through Hydrogel for Higher Lithium Storages.

Transition metal phosphides (TMPs) have gained increased attention in energy storage due to their potential applications for optimizing electrochemical performances. However, their preparation routes usually require highly toxic and flammable phosphorus sources with strict reaction conditions. The existence of multiple energetically favorable stoichiometries also makes it a challenge to achieve phase control of metal phosphides. In this work, we have successfully realized the phase-controllable framework of cobalt phosphide from Co2P to CoP by employing a semi-interpenetrating network (semi-IPN) hydrogel as a precursor. Interestingly, the semi-IPN hydrogel could serve as a self-assembly/sacrificing template to accomplish 3D space confinement, where poly(vinylphosphonic acid) (PVPA) was identified as a prominent phosphorus source due to its strong metal complexation ability and high thermal stability. Furthermore, this route is successfully extended to the synthesis of other TMPs, including Fe2P, Ni2P, and Cu3P. The specific structure of cobalt phosphides gives rise to superior lithium storage performance, showing superior cycling stability (495.2 mAh g-1 after 1000 cycles at 2.0 A g-1). This approach envisions a new outlook on exploitation of essential functional hydrogels for the creation of inorganic materials toward sustainable energy development.

Real-time quantitative nicking endonuclease-mediated isothermal amplification with small molecular beacons.

Techniques of isothermal amplification have recently made great strides, and have generated significant interest in the field of point-of-care detection. Nicking endonuclease-mediated isothermal amplification (NEMA) is an example of simple isothermal technology. In this paper, a real-time quantitative nicking endonuclease-mediated isothermal amplification with small molecular beacons (SMB-NEMA) of improved specificity and sensitivity is described. First, we optimized the prohibition of de novo synthesis by choosing Nt·BstNBI endonuclease. Second, the whole genome was successfully amplified with Nt·BstNBI (6 U), betaine (1 M) and trehalose (60 mM) for the first time. Third, we achieved 10 pg sensitivity for the first time after adding a small molecular beacon that spontaneously undergoes a conformational change when hybridizing to target, and the practical test validated the assay's application. The small molecular beacon has a similar melting temperature to the reaction temperature, but is approximately 10 bp shorter than the length of a traditional molecular beacon. A new threshold regulation was also established for isothermal conditions. Finally, we established a thermodynamic model for designing small molecular beacons. This multistate model is more correct than the traditional algorithm. This theoretical and practical basis will help us to monitor SMB-NEMA in a quantitative way. In summary, our SMB-NEMA method allows the simple, specific and sensitive assessment of isothermal DNA quantification.

On-Chip Micro Temperature Controllers Based on Freestanding Thermoelectric Nano Films for Low-Power Electronics.

Multidimensional integration and multifunctional component assembly have been greatly explored in recent years to extend Moore's Law of modern microelectronics. However, this inevitably exacerbates the inhomogeneity of temperature distribution in microsystems, making precise temperature control for electronic components extremely challenging. Herein, we report an on-chip micro temperature controller including a pair of thermoelectric legs with a total area of 50 × 50 µm2, which are fabricated from dense and flat freestanding Bi2Te3-based thermoelectric nano films deposited on a newly developed nano graphene oxide membrane substrate. Its tunable equivalent thermal resistance is controlled by electrical currents to achieve energy-efficient temperature control for low-power electronics. A large cooling temperature difference of 44.5 K at 380 K is achieved with a power consumption of only 445 µW, resulting in an ultrahigh temperature control capability over 100 K mW-1. Moreover, an ultra-fast cooling rate exceeding 2000 K s-1 and excellent reliability of up to 1 million cycles are observed. Our proposed on-chip temperature controller is expected to enable further miniaturization and multifunctional integration on a single chip for microelectronics.

Efficacy of Different Exercises on Mild to Moderate Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis.

PURPOSE: The aims of this study are to evaluate the effectiveness of different exercise interventions on patients with adolescent idiopathic scoliosis and to provide evidence-based exercise prescriptions for this population. METHODS: The PubMed, Embase, Cochrane Library, Web of Science, CNKI, Chinese Biomedical Literature Database (CBM), VIP, and Wanfang Data Knowledge Service Platform were searched until January 2023. The data were pooled and a meta-analysis was conducted. RESULTS: A total of 19 studies were conducted with 778 participants. The Schroth exercises group (mean difference = -3.48, 95% confidence interval = -4.73 to -2.23, P < 0.00001) and strength training group (mean difference = -3.43, 95% confidence interval = -4.06 to -2.80, P < 0.00001) had better recovery of the Cobb angle than the other groups. The Cobb angle rehabilitation effect was good in the time of less than 60-min group. In addition, there was no significant difference found between the different intervention periods groups ( P > 0.05). CONCLUSIONS: Schroth exercise and strength training significantly improved Cobb angle of adolescent idiopathic scoliosis patients; exercising for less than 60 mins is effective for Cobb angle rehabilitation, but prolonging exercise time cannot improve training effectiveness; 12 wks of exercise significantly improved Cobb angle, but prolonged training periods did not have a significant impact.

Single universal primer multiplex ligation-dependent probe amplification with sequencing gel electrophoresis analysis.

In this study, a novel single universal primer multiplex ligation-dependent probe amplification (SUP-MLPA) technique that uses only one universal primer to perform multiplex polymerase chain reaction (PCR) was developed. Two reversely complementary common sequences were designed on the 5' or 3' end of the ligation probes (LPs), which allowed the ligation products to be amplified through only a single universal primer (SUP). SUP-MLPA products were analyzed on sequencing gel electrophoresis with extraordinary resolution. This method avoided the high expenses associated with capillary electrophoresis, which was the commonly used detection instrument. In comparison with conventional multiplex PCR, which suffers from low sensitivity, nonspecificity, and amplification disparity, SUP-MLPA had higher specificity and sensitivity and a low detection limit of 0.1 ng for detecting single crop species when screening the presence of genetically modified crops. We also studied the effect of different lengths of stuffer sequences on the probes for the first time. Through comparing the results of quantitative PCR, the LPs with different stuffer sequences did not affect the ligation efficiency, which further increased the multiplicity of this assay. The improved SUP-MLPA and sequencing gel electrophoresis method will be useful for food and animal feed identification, bacterial detection, and verification of genetic modification status of crops.

How Ice Rink Locations Affect Performance Time in Short-Track Speed Skating.

Purpose: To accurately provide evaluations on how match performance for elite skaters in short track speed skating developed, and whether geographical factors of ice rink locations should be considered apart from technical abilities. We created a dataset containing competition records from the 2013-14 to 2020-21 seasons (500 m event) on the official website. Methods: One-way ANOVA was applied to statistically analyze whether the best performance times exhibited significant differences in varied hosting cities. Performance-time matrix and multivariate regression model were further established to quantitatively explain how geographical factors (longitude, latitude, altitude, and barometric pressure) affected performance. Results: Our findings firstly confirmed that the fastest 500 m finishing times varied due to the hosting cities (P = 0.008) and showed that venue locations could boost or impair performance time with the maximum range of 3.6 s. Meanwhile, latitude (slightly over 46° when performance is maximized) was the most influential factor to account for the performance-time difference in different ice rink locations according to the multivariate regression model, though altitude (1,225 meters when performance is maximized) was also important. Conclusions: In this perspective, elite skaters should check the geographical factors of the venues before they participated in the upcoming competitions, assess the real strength of their rivals, and adopt flexible tactics during training sessions.

Champion Position Analysis in Short Track Speed Skating Competitions From 2007 to 2019.

Purpose: Short track speed skating is a racing sport with racing tactics are equally crucial to speed and technical skating skills. Therefore, to investigate the relationship between starting and finishing positions for elite skaters and subsequently, explore pacing patterns for champions are necessary. Methods: To investigate a pattern of effective tactical positioning strategy, Kendall's tau-b correlations between starting and finishing position were calculated, with 500 m races having the most positive correlation (0.347, P < 0.05). Results: Furthermore, starting position distributions of winners in each round, as well as the fluctuations in champion starting positions across rounds were analyzed. Our findings showed that skaters on the first track were inclined to win the rounds in 500, 1,000, and 1,500 m (28, 28, and 22%, respectively), and the differences between starting and finishing positions for champions were minimized in semi-finals. Meanwhile, the pacing patterns were gaining more fluctuations by the increase of race distances for champions, as the average standard deviation of lap rankings equaled 0.90, 1.15, and 2.21 for 500, 1,000, and 1,500 m races, respectively. Conclusion: In conclusion, elite skaters should adopt flexible tactics at the lowest cost of energy consumption. The overall variability of lap ranking in long-distance races were distinctly higher than it in short distance.

Advanced Hierarchical Vesicular Carbon Co-Doped with S, P, N for High-Rate Sodium Storage.

Hierarchical nanoscale carbons have received wide interest as electrode materials for energy storage and conversion due to their fast mass transfer processes, outstanding electronic conductivity, and high stability. Here, heteroatom (S, P, and N) doped hierarchical vesicular carbon (HHVC) materials with a high surface area up to 867.5 m2 g-1 are successfully prepared using a surface polymerization of hexachloro-cyclotriphosphazene (HCCP) and 4,4'-sulfonyldiphenol (BPS) on the ZIF-8 polyhedrons. Significantly, it is the first time to achieve a controllability of the wall thickness for this unique carbon, ranging from 18 to 52 nm. When utilized as anodes for sodium ion batteries, these novel carbon materials exhibit a high specific capacity of 327.2 mAh g-1 at 100 mA g-1 after 100 cycles, which can be attributed to the expanded interlayer distance and enhanced conductivity derived from the doping of heteroatoms. Importantly, a high capacity of 142.6 mAh g-1 can be obtained even at a high current density of 5 A g-1, assigning to fast ion/electronic transmission processes stemming from the unique hierarchical vesicular structure. This work offers a new route for the fabrication/preparation of multi-heteroatom doped hierarchical vesicular materials.

Multidimensional Evolution of Carbon Structures Underpinned by Temperature-Induced Intermediate of Chloride for Sodium-Ion Batteries.

Different dimensions of carbon materials with various features have captured numerous interests due to their applications on the tremendous fields. Restricted by the raw materials and devices, the controlling of their morphology is a major challenge. Utilizing the catalytic features of the intermediates from the low-cost salts and polymerization of 0D carbon quantum dots (CQDs), 0D CQDs are expected to self-assemble into 1/2/3D carbon structures with the assistance of temperature-induced intermediates (e.g., ZnO, Ni, and Cu) from the salts (ZnCl2, NiCl2, and CuCl). The formation mechanisms are illustrated as follows: 1) the "orient induction" to evoke "vine style" growth mechanism of ZnO; 2) the "dissolution-precipitation" of Ni; and 3) the "surface adsorption self-limited" of Cu. Subsequently, the degree of graphitization, interlayer distance, and special surface area are investigated in detail. 1D structure from 700 °C as anode displays a high Na-storage capacity of 301.2 mAh g-1 at 0.1 A g-1 after 200 cycles and 107 mAh g-1 at 5.0 A g-1 after 5000 cycles. Quantitative kinetics analysis confirms the fundamentals of the enhanced rate capacity and the potential region of Na-insertion/extraction. This elaborate work opens up an avenue toward the design of carbon with multidimensions and in-depth understanding of their sodium-storage features.