Detalhe da pesquisa
1.
Novel (E)-3-(3-Oxo-4-substituted-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-N-hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Bioevaluation.
Chem Biodivers
; 20(5): e202201030, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017259
2.
Design, synthesis, and evaluation of novel (E)-N'-(3-allyl-2-hydroxy)benzylidene-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as antitumor agents.
Arch Pharm (Weinheim)
; 355(1): e2100216, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34674294
3.
Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents.
Bioorg Med Chem Lett
; 30(22): 127537, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32916298
4.
Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.
Bioorg Chem
; 101: 103988, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32534346
5.
Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents.
J Enzyme Inhib Med Chem
; 35(1): 1854-1865, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32981382
6.
New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity.
Chem Biodivers
; 17(3): e1900670, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943757
7.
Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.
Bioorg Chem
; 92: 103202, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31479984
8.
Quinazolin-4(3H)-one-Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.
Chem Biodivers
; 16(4): e1800502, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653817
9.
Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents.
Bioorg Chem
; 76: 258-267, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29223029
10.
N'-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity.
Chem Biodivers
; 15(10): e1800322, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054973
11.
Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.
Chem Biodivers
; 15(6): e1800027, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29667768
12.
Novel N-hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicity.
Bioorg Chem
; 71: 160-169, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196602
13.
Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3-yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents.
Anticancer Agents Med Chem
; 22(14): 2586-2598, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35040418
14.
Novel Conjugated Quinazolinone-Based Hydroxamic Acids: Design, Synthesis and Biological Evaluation.
Med Chem
; 17(7): 732-749, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32310052
15.
Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation.
ACS Omega
; 6(7): 4907-4920, 2021 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33644598
16.
Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy) methyl)-N-hydroxybenzamides/propenamides as Histone Deacetylase Inhibitors and Antitumor Agents.
Anticancer Agents Med Chem
; 19(4): 546-556, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30426904
17.
Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis.
Med Chem
; 14(8): 831-850, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29807520