Detalhe da pesquisa
1.
Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis.
Protein Expr Purif
; 193: 106047, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35026386
2.
The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
Molecules
; 26(10)2021 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34070212
3.
NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
J Biomol NMR
; 74(10-11): 595-611, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32761504
4.
Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.
J Biol Chem
; 289(29): 19869-80, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24860094
5.
Histone deacetylases as regulators of inflammation and immunity.
Trends Immunol
; 32(7): 335-43, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570914
6.
Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 10): 1981-94, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100317
7.
The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 10): 1290-302, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993083
8.
Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
Acta Crystallogr D Struct Biol
; 78(Pt 1): 75-90, 2022 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34981764
9.
The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.
Acta Crystallogr D Struct Biol
; 78(Pt 3): 337-352, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35234148
10.
Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets.
PLoS One
; 15(11): e0241306, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33216758
11.
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity.
J Med Chem
; 63(2): 529-541, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31910011
12.
Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation.
Biochemistry
; 48(35): 8466-72, 2009 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19642650
13.
The atypical thiol-disulfide exchange protein α-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase.
Acta Crystallogr D Struct Biol
; 75(Pt 3): 283-295, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30950399
14.
Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development.
PLoS One
; 14(9): e0222595, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31536549
15.
Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Nat Commun
; 10(1): 976, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30824772
16.
A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Nat Commun
; 8: 16065, 2017 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28722010
17.
Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a.
Nat Commun
; 8(1): 351, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28839129
18.
Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system.
ACS Chem Biol
; 10(4): 957-64, 2015 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25603425
19.
Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence.
J Med Chem
; 58(2): 577-87, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25470204
20.
Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo.
Antioxid Redox Signal
; 20(4): 606-17, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901809