Detalhe da pesquisa
1.
N-glycosylation is a potent regulator of prion protein neurotoxicity.
J Biol Chem
; 299(9): 105101, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507020
2.
Obesity: a perfect storm for carcinogenesis.
Cancer Metastasis Rev
; 41(3): 491-515, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36038791
3.
Mechanisms of prion-induced toxicity.
Cell Tissue Res
; 392(1): 81-96, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070155
4.
Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects.
Nat Chem Biol
; 17(1): 20-29, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747812
5.
Intrinsic toxicity of the cellular prion protein is regulated by its conserved central region.
FASEB J
; 34(6): 8734-8748, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32385908
6.
Sleeve gastrectomy enhances glucose utilization and remodels adipose tissue independent of weight loss.
Am J Physiol Endocrinol Metab
; 318(5): E678-E688, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32069072
7.
Prions activate a p38 MAPK synaptotoxic signaling pathway.
PLoS Pathog
; 14(9): e1007283, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30235355
8.
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Acta Neuropathol
; 139(3): 503-526, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31853635
9.
Cellular prion protein targets amyloid-ß fibril ends via its C-terminal domain to prevent elongation.
J Biol Chem
; 292(41): 16858-16871, 2017 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28842494
10.
A Neuronal Culture System to Detect Prion Synaptotoxicity.
PLoS Pathog
; 12(5): e1005623, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27227882
11.
Identification of Anti-prion Compounds using a Novel Cellular Assay.
J Biol Chem
; 291(50): 26164-26176, 2016 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27803163
12.
Synthetic Prions Provide Clues for Understanding Prion Diseases.
Am J Pathol
; 186(4): 761-4, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26854642
13.
Mechanisms of prion-induced neurodegeneration.
Expert Rev Mol Med
; 18: e5, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055367
14.
A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes.
J Biol Chem
; 289(43): 30144-60, 2014 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25217642
15.
The neuroprotective effect of Klotho is mediated via regulation of members of the redox system.
J Biol Chem
; 289(35): 24700-15, 2014 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25037225
16.
A novel student-led approach to multiple-choice question generation and online database creation, with targeted clinician input.
Teach Learn Med
; 27(2): 182-8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25893940
17.
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.
J Neurosci
; 33(6): 2408-18, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23392670
18.
An N-terminal fragment of the prion protein binds to amyloid-ß oligomers and inhibits their neurotoxicity in vivo.
J Biol Chem
; 288(11): 7857-7866, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23362282
19.
Sigma Receptor Ligands Are Potent Antiprion Compounds that Act Independently of Sigma Receptor Binding.
ACS Chem Neurosci
; 15(11): 2265-2282, 2024 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743607
20.
New role of fat-free mass in cancer risk linked with genetic predisposition.
Sci Rep
; 14(1): 7270, 2024 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38538606