Detalhe da pesquisa
1.
Filipin complex-reactive brain lesions: a cautionary tale.
Neuropathol Appl Neurobiol
; : e12950, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38112248
2.
Modifying Dietary Protein Impacts mTOR Signaling and Brain Deposition of Amyloid ß in a Knock-In Mouse Model of Alzheimer Disease.
J Nutr
; 153(5): 1407-1419, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870538
3.
Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus.
Eur J Neurosci
; 47(9): 1043-1053, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570886
4.
Slow, continuous enzyme replacement via spinal CSF in dogs with the paediatric-onset neurodegenerative disease, MPS IIIA.
J Inherit Metab Dis
; 40(3): 443-453, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27832416
5.
A novel conditional Sgsh knockout mouse model recapitulates phenotypic and neuropathic deficits of Sanfilippo syndrome.
J Inherit Metab Dis
; 40(5): 715-724, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28451919
6.
Low-dose, continuous enzyme replacement therapy ameliorates brain pathology in the neurodegenerative lysosomal disorder mucopolysaccharidosis type IIIA.
J Neurochem
; 137(3): 409-22, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762778
7.
Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice.
Mol Genet Metab
; 115(1): 33-40, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25795516
8.
Evaluation of enzyme dose and dose-frequency in ameliorating substrate accumulation in MPS IIIA Huntaway dog brain.
J Inherit Metab Dis
; 38(2): 341-50, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25421091
9.
Disease stage determines the efficacy of treatment of a paediatric neurodegenerative disease.
Eur J Neurosci
; 39(12): 2139-50, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25068161
10.
Development of cerebellar pathology in the canine model of mucopolysaccharidosis type IIIA (MPS IIIA).
Mol Genet Metab
; 113(4): 283-93, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453402
11.
Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer's disease.
IBRO Neurosci Rep
; 12: 131-141, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35146484
12.
Enzyme replacement reduces neuropathology in MPS IIIA dogs.
Neurobiol Dis
; 43(2): 422-34, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550404
13.
Inhibiting mTOR activity using AZD2014 increases autophagy in the mouse cerebral cortex.
Neuropharmacology
; 190: 108541, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794244
14.
Measurement of autophagic flux in humans: an optimized method for blood samples.
Autophagy
; 17(10): 3238-3255, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33164641
15.
The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life.
Cell Rep
; 36(8): 109564, 2021 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433065
16.
Lysosomal Dysregulation in the Murine AppNL-G-F/NL-G-F Model of Alzheimer's Disease.
Neuroscience
; 429: 143-155, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31917339
17.
Examination of intravenous and intra-CSF protein delivery for treatment of neurological disease.
Eur J Neurosci
; 29(6): 1197-214, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19302155
18.
Reduction in open field activity in the absence of memory deficits in the AppNL-G-F knock-in mouse model of Alzheimer's disease.
Behav Brain Res
; 336: 177-181, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28887197
19.
Axonal dystrophy in the brain of mice with Sanfilippo syndrome.
Exp Neurol
; 295: 243-255, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28601604
20.
Continual Low-Dose Infusion of Sulfamidase Is Superior to Intermittent High-Dose Delivery in Ameliorating Neuropathology in the MPS IIIA Mouse Brain.
JIMD Rep
; 29: 59-68, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26620043