Detalhe da pesquisa
1.
Spatially resolved clonal copy number alterations in benign and malignant tissue.
Nature
; 608(7922): 360-367, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948708
2.
Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL.
Blood
; 141(26): 3166-3183, 2023 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084385
3.
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
Cell
; 142(1): 65-76, 2010 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20603015
4.
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34479993
5.
Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir.
J Biol Chem
; 298(8): 102169, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732208
6.
Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming.
J Transl Med
; 21(1): 169, 2023 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36869333
7.
Mitotic MTH1 Inhibitors in Treatment of Cancer.
Cancer Treat Res
; 186: 223-237, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37978139
8.
Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
Mol Cell
; 60(1): 163-76, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344098
9.
PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription.
Mol Cell
; 59(6): 984-97, 2015 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26321255
10.
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
J Biol Chem
; 296: 100568, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753169
11.
NUDT1 promotes the accumulation and longevity of CD103+ TRM cells in primary biliary cholangitis.
J Hepatol
; 77(5): 1311-1324, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753523
12.
Precision oncology using ex vivo technology: a step towards individualised cancer care?
Expert Rev Mol Med
; 24: e39, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184897
13.
Development of a chemical probe against NUDT15.
Nat Chem Biol
; 16(10): 1120-1128, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690945
14.
Pathways of mammalian replication fork restart.
Nat Rev Mol Cell Biol
; 11(10): 683-7, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20842177
15.
Cell Cycle Profiling Reveals Protein Oscillation, Phosphorylation, and Localization Dynamics.
Mol Cell Proteomics
; 19(4): 608-623, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051232
16.
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Res
; 48(21): 12234-12251, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33211885
17.
The scaffold protein WRAP53ß orchestrates the ubiquitin response critical for DNA double-strand break repair.
Genes Dev
; 28(24): 2726-38, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512560
18.
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
J Biol Chem
; 295(33): 11656-11668, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571877
19.
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
J Biol Chem
; 295(15): 4761-4772, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144205
20.
ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.
EMBO J
; 36(14): 2161-2176, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607002