Detalhe da pesquisa
1.
Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice.
J Biol Chem
; 300(2): 105655, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237682
2.
Neuraminidase 4 (NEU4): new biological and physiological player.
Glycobiology
; 33(3): 182-187, 2023 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36728702
3.
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells.
Arterioscler Thromb Vasc Biol
; 40(7): 1664-1679, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32434409
4.
Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice.
J Biol Chem
; 293(38): 14689-14706, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30097518
5.
Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained.
J Biol Chem
; 293(19): 7329-7343, 2018 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29593095
6.
Neuronal pentraxin 1 depletion delays neurodegeneration and extends life in Sandhoff disease mice.
Hum Mol Genet
; 26(4): 661-673, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007910
7.
Asialoglycoprotein receptors as important mediators of plasma lipids and atherosclerosis.
Curr Opin Lipidol
; 28(2): 209-212, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28092276
8.
Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice.
Hum Mol Genet
; 22(19): 3960-75, 2013 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23727835
9.
The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double knockout mice.
Arterioscler Thromb Vasc Biol
; 34(11): 2394-403, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25212235
10.
Miglustat as a therapeutic agent: prospects and caveats.
J Med Genet
; 49(9): 591-7, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22892202
11.
Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice.
J Lipid Res
; 53(12): 2573-85, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22984145
12.
The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis.
Mol Genet Metab
; 107(1-2): 173-85, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22898113
13.
Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium.
Front Physiol
; 13: 1023397, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36714321
14.
Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance.
Nat Commun
; 13(1): 770, 2022 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35140212
15.
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity.
Kidney360
; 3(8): 1394-1410, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36176646
16.
A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency.
Mol Genet Metab
; 97(1): 43-52, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19217813
17.
Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice.
JHEP Rep
; 1(6): 418-429, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32039393
18.
Suppression of NK and CD8+ T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease.
J Neuroimmunol
; 306: 55-67, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28385189
19.
Bi-phasic gliosis drives neuropathology in a Sandhoff disease mouse model.
J Neuroimmunol
; 299: 19-27, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27725117
20.
Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth.
J Am Heart Assoc
; 5(8)2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27528409