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Arch Pathol Lab Med ; 126(12): 1530-3, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12456217

RESUMO

Adrenal tumors often present with clinical features that are specific and unique to their endocrine metabolism. When these features are in conflict with the pathologic appearance of the tumor, there can be great consternation for both the pathologist and the surgeon. In the case reported herein, an adrenalectomy was performed for clinical features of pheochromocytoma that on gross and histologic examination had the pathologic features of an adrenal cortical adenoma. Electron microscopy subsequently revealed that the tumor cells contained adrenalin-type granules, explaining the clinical outcome. It is crucial for both the surgeon and the surgical pathologist to be aware of this possibility when the clinical and pathologic features of an adrenal tumor are not congruent.


Assuntos
Neoplasias do Córtex Suprarrenal/patologia , Neoplasias das Glândulas Suprarrenais/patologia , Adenoma Adrenocortical/patologia , Epinefrina/metabolismo , Feocromocitoma/patologia , Vesículas Secretórias/patologia , Neoplasias do Córtex Suprarrenal/ultraestrutura , Neoplasias das Glândulas Suprarrenais/ultraestrutura , Adenoma Adrenocortical/ultraestrutura , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Feocromocitoma/ultraestrutura , Vesículas Secretórias/ultraestrutura
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