Detalhe da pesquisa
1.
PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
Hum Mol Genet
; 30(17): 1607-1617, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34075397
2.
Regulation of MST complexes and activity via SARAH domain modifications.
Biochem Soc Trans
; 49(2): 675-683, 2021 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33860801
3.
A novel direct spray-from-tissue ionization method for mass spectrometric analysis of human brain tumors.
Anal Bioanal Chem
; 407(25): 7797-805, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26277186
4.
Development and Utility of a PAK1-Selective Degrader.
J Med Chem
; 65(23): 15627-15641, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416208
5.
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
Mol Cancer Res
; 20(5): 699-711, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082167
6.
Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2).
BMC Pharmacol Toxicol
; 20(1): 67, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730023
7.
Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay.
J Vis Exp
; (140)2018 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30394375