Detalhe da pesquisa
1.
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Nature
; 629(8013): 927-936, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588697
2.
Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer.
Cancer Res
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38695869
3.
Notch Signaling Regulates Immunosuppressive Tumor-Associated Macrophage Function in Pancreatic Cancer.
Cancer Immunol Res
; 12(1): 91-106, 2024 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931247
4.
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.
Nat Commun
; 15(1): 1532, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38378697
5.
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy.
Res Sq
; 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398248
6.
Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer.
bioRxiv
; 2023 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711890
7.
Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer.
Cancer Discov
; 13(2): 298-311, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36472553
8.
KRT17High/CXCL8+ tumor cells display both classical and basal features and regulate myeloid infiltration in the pancreatic cancer microenvironment.
Clin Cancer Res
; 2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37851080
9.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
bioRxiv
; 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105998
10.
Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming.
Cell Mol Gastroenterol Hepatol
; 13(6): 1673-1699, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245687
11.
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Elife
; 112022 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35815941
12.
Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer.
Cell Mol Gastroenterol Hepatol
; 12(5): 1531-1542, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303882
13.
The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice.
Cell Mol Gastroenterol Hepatol
; 11(2): 349-369, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32882403
14.
Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1.
Cancer Res
; 81(16): 4305-4318, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049975
15.
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Life Sci Alliance
; 4(6)2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782087
16.
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.
Cancer Cell
; 39(9): 1227-1244.e20, 2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297917
17.
Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
Clin Cancer Res
; 27(7): 2023-2037, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495315
18.
Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis.
Cancer Discov
; 10(3): 422-439, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31911451
19.
Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer.
Nat Cancer
; 1(11): 1097-1112, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34296197
20.
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Cell Metab
; 29(6): 1390-1399.e6, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827862