Detalhe da pesquisa
1.
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Am J Physiol Heart Circ Physiol
; 321(2): H382-H389, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34142888
2.
The integrin αvß6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.
J Pathol
; 249(3): 332-342, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31259422
3.
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.
Proc Natl Acad Sci U S A
; 114(3): E317-E326, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28053233
4.
The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs).
Semin Cell Dev Biol
; 50: 125-32, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26791049
5.
Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-ß Production.
J Immunol
; 195(4): 1753-62, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26170386
6.
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
Proc Natl Acad Sci U S A
; 111(51): 18267-72, 2014 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25489104
7.
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-like receptor (TLR)-induced cytokine production.
J Biol Chem
; 289(4): 2112-26, 2014 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311790
8.
Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.
PLoS Genet
; 7(8): e1002238, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21901106
9.
Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae.
J Biol Chem
; 286(49): 42037-42050, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22006927
10.
Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways.
J Biol Chem
; 286(44): 38018-38026, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908610
11.
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6.
Oncogene
; 41(20): 2811-2823, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35418690
12.
Cross-talk between the p38alpha and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation.
J Biol Chem
; 285(34): 25928-40, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20547488
13.
DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5.
Cell Signal
; 20(5): 836-43, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18280112
14.
The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5.
Biochem J
; 411(3): 613-22, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18248330
15.
Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
Biochem J
; 412(2): 287-98, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321244
16.
Dual-specificity MAP kinase phosphatases in health and disease.
Biochim Biophys Acta Mol Cell Res
; 1866(1): 124-143, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401534
17.
Does MK5 reconcile classical and atypical MAP kinases?
Front Biosci
; 13: 4617-24, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18508533
18.
Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5.
Mol Cell Biol
; 25(5): 1830-45, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15713638
19.
The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development.
Mol Cell Biol
; 25(18): 8323-33, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16135819
20.
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
Curr Biol
; 13(12): 1009-18, 2003 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12814546