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1.
Opt Lett ; 44(12): 3002-3005, 2019 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-31199366

RESUMO

We demonstrate a novel way to form and deplete a vapor-cell magneto-optic trap (MOT) using a reversible, solid-state alkali-metal source via an applied polarized voltage. Using ∼100 mW of electrical power, a trapped-atom number of 5×106 has been achieved, starting from near zero and the timescales of the MOT formation and depletion of ∼1 s. This fast, reversible, and low-power alkali-atom source is desirable in both tabletop and portable cold-atom systems. The core technology of this device should translate readily to other alkali and alkaline-earth elements that could find a wide range of uses in cold-atom systems and instruments.

2.
Phys Rev Lett ; 122(11): 113601, 2019 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-30951321

RESUMO

Sophisticated Ramsey-based interrogation protocols using composite laser pulse sequences have been recently proposed to provide next-generation high-precision atomic clocks with a near perfect elimination of frequency shifts induced during the atom-probing field interaction. We propose here a simple alternative approach to the autobalanced Ramsey interrogation protocol and demonstrate its application to a cold-atom microwave clock based on coherent population trapping (CPT). The main originality of the method, based on two consecutive Ramsey sequences with different dark periods, is to sample the central Ramsey fringes with frequency jumps finely adjusted by an additional frequency-displacement concomitant parameter, scaling as the inverse of the dark period. The advantage of this displaced frequency-jump Ramsey method is that the local oscillator (LO) frequency is used as a single physical variable to control both servo loops of the sequence, simplifying its implementation and avoiding noise associated with controlling the LO phase. When tested using a CPT cold-atom clock, the DFJR scheme reduces the sensitivity of the clock frequency to variations of the light shifts by more than an order of magnitude compared with the standard Ramsey interrogation. This simple method can be applied in a wide variety of Ramsey-spectroscopy based applications including frequency metrology with CPT-based and optical atomic clocks, mass spectrometry, and precision spectroscopy.

3.
Proc Natl Acad Sci U S A ; 105(7): 2286-90, 2008 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-18287080

RESUMO

We demonstrate remote detection of nuclear magnetic resonance (NMR) with a microchip sensor consisting of a microfluidic channel and a microfabricated vapor cell (the heart of an atomic magnetometer). Detection occurs at zero magnetic field, which allows operation of the magnetometer in the spin-exchange relaxation-free (SERF) regime and increases the proximity of sensor and sample by eliminating the need for a solenoid to create a leading field. We achieve pulsed NMR linewidths of 26 Hz, limited, we believe, by the residence time and flow dispersion in the encoding region. In a fully optimized system, we estimate that for 1 s of integration, 7 x 10(13) protons in a volume of 1 mm(3), prepolarized in a 10-kG field, can be detected with a signal-to-noise ratio of approximately 3. This level of sensitivity is competitive with that demonstrated by microcoils in 100-kG magnetic fields, without requiring superconducting magnets.

4.
Science ; 175(4021): 524-7, 1972 Feb 04.
Artigo em Inglês | MEDLINE | ID: mdl-17755654

RESUMO

Tetrapod skeletons recently found in the Fremouw Formation in the Shackleton Glacier area, Transantarctic Mountains, include several forms that closely compare to South African species. Faunal similarities that confirm a close connection between Antarctica and Africa during the Triassic Period lend further support to the concept of Gondwanaland and continental drift.

5.
Onderstepoort J Vet Res ; 75(2): 147-52, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18788208

RESUMO

Pigeon paramyxovirus type 1 (PPMV-1), a variant of Newcastle disease virus that primarily affects doves and pigeons has been isolated in South Africa since the mid-1980s. Phylogenetic evidence indicates that pigeon paramyxovirus type 1 viruses were introduced into South Africa on multiple occasions, based on the presence of two separate lineages, 4bi and 4bii, that have been circulating in Europe and the Far East since the early 1990s. During 2006, a PPMV-1 virus was isolated from an African ground hornbill (Bucorvus leadbeateri) which became acutely infected with PPMV-1 and died, probably after scavenging off infected dove carcasses in the region, since a closely-related PPMV-1 strain was also isolated from doves collected nearby. The hornbill isolate had ICPI and MDT values characteristic of PPMV-1 strains. The threat of PPMV-1 to poultry production and biodiversity in southern Africa highlights the importance of monitoring the spread of this strain.


Assuntos
Columbidae/virologia , Doença de Newcastle/virologia , Vírus da Doença de Newcastle/classificação , Vírus da Doença de Newcastle/isolamento & purificação , Filogenia , Sequência de Aminoácidos , Animais , Cadeia Alimentar , Dados de Sequência Molecular , Doença de Newcastle/epidemiologia , Doença de Newcastle/transmissão , Vírus da Doença de Newcastle/patogenicidade , RNA Viral/análise , Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária , Alinhamento de Sequência , África do Sul/epidemiologia , Especificidade da Espécie
6.
Rev Sci Instrum ; 78(8): 083102, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17764308

RESUMO

We have designed and tested a set of five miniature nested magnetic shields constructed of high-permeability material, with external volumes for the individual shielding layers ranging from 0.01 to 2.5 cm(3). We present measurements of the longitudinal and transverse shielding factors (the ratio of external to internal magnetic field) of both individual shields and combinations of up to three layers. The largest shielding factor measured was 6 x 10(6) for a nested set of three shields, and from our results we predict a shielding factor of up to 1 x 10(13) when all five shields are used. Two different techniques were used to measure the internal field: a chip-scale atomic magnetometer and a commercially available magnetoresistive sensor. Measurements with the two methods were in good agreement.


Assuntos
Magnetismo/instrumentação , Modelos Teóricos , Proteção Radiológica/instrumentação , Radiometria/métodos , Simulação por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Miniaturização , Doses de Radiação , Proteção Radiológica/métodos
7.
Appl Phys Lett ; 110(3): 031106, 2017 Jan 16.
Artigo em Inglês | MEDLINE | ID: mdl-28179732

RESUMO

We report on the development of a microfabricated atomic magnetic gradiometer based on optical spectroscopy of alkali atoms in the vapor phase. The gradiometer, which operates in the spin-exchange relaxation free regime, has a length of 60 mm and cross sectional diameter of 12 mm, and consists of two chip-scale atomic magnetometers which are interrogated by a common laser light. The sensor can measure differences in magnetic fields, over a 20 mm baseline, of 10 fT/[Formula: see text] at frequencies above 20 Hz. The maximum rejection of magnetic field noise is 1000 at 10 Hz. By use of a set of compensation coils wrapped around the sensor, we also measure the sensor sensitivity at several external bias field strengths up to 150 mG. This device is useful for applications that require both sensitive gradient field information and high common-mode noise cancellation.

8.
Opt Express ; 13(4): 1249-53, 2005 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-19494996

RESUMO

We demonstrate a microfabricated atomic clock physics package based on coherent population trapping (CPT) on the D1 line of 87Rb atoms. The package occupies a volume of 12 mm3 and requires 195 mW of power to operate at an ambient temperature of 200 degrees C. Compared to a previous microfabricated clock exciting the D2 transition in Cs [1], this 87Rb clock shows significantly improved short- and long-term stability. The instability at short times is 4 x?10-11 / tau?/2 and the improvement over the Cs device is due mainly to an increase in resonance amplitude. At longer times (tau?> 50 s), the improvement results from the reduction of a slow drift to ?5 x 10-9 / day. The drift is most likely caused by a chemical reaction of nitrogen and barium inside the cell. When probing the atoms on the D1 line, spin-exchange collisions between Rb atoms and optical pumping appear to have increased importance compared to the D2 line.

9.
Artigo em Inglês | MEDLINE | ID: mdl-18238650

RESUMO

The performance of a simple microwave frequency reference based on Raman scattering in an atomic vapor is examined. This reference has the potential to be compact, low-power, and insensitive to acceleration. Several design architectures have been evaluated with a table-top experiment in order to guide the future development of a compact system. Fractional frequency deviations of

10.
Artigo em Inglês | MEDLINE | ID: mdl-18238656

RESUMO

Phase noise measurements of an optoelectronic oscillator (OEO) at frequencies less than 10 Ha from the carrier (10.6 GHz) as well as the measured Allan variance are presented for the first time. The system has a measured single-side-band (SSB) phase-noise of -123 dB/Hz at 10 kHz from the carrier and a sigma(y)(tau)=10(-10) for an integration time between 1 and 10 seconds. The importance of amplifier phase-noise and environmental fluctuations in determining the noise of the oscillator at these low Fourier frequencies is verified experimentally and analyzed using a generalized model of noise sources in the OEOs. This analysis then allows prediction of the oscillator performance from measured parameters of individual components in the system.

11.
Biol Trace Elem Res ; 8(2): 79-91, 1985 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24257868

RESUMO

In this study of inter- and intrasubject variance of trace element (TE) dietary intake data, 14 female university students recorded weighed, self-selected food intakes for seven consecutive days, starting on a randomly selected day of the week. Daily intakes of energy, dietary fiber, macronutrients, 7 vitamins, and Fe, Zn, Cu, Mn, and Se were calculated using food composition tables and literature values. Analysis of variance showed a significant weekend effect for energy and TE intakes that was reduced when data were expressed on the basis of nutrient densities. No day of the working week or training effect was noted for energy or any nutrient. The ratios of the inter- to intrasubject coefficient of variation for all the nutrients were surprisingly constant. However, the overall coefficients of variation-Fe, 36.5%; Zn, 45.7%; Cu, 43.7%; Mn, 58.2%, and Se, 52.7%-were markedly lower than for vitamin A (109.0%), Vitamin D (117.1%), and linoleic acid (82.2%), but slightly higher than those for energy (27.2%) and carbohydrate (30.1%). The widespread distribution of TE in the diets results in comparable reliability for dietary studies of TE and macronutrients. The 95% confidence intervals for mean individual TE intakes ranged from 25% (Zn) to 40% (Se). These relatively large uncertainties make it essential that any assessment of the significance of correlations between dietary TE intakes and biochemical indices takes into account the intra-individual variation associated with both variables.

12.
Onderstepoort J Vet Res ; 59(2): 135-44, 1992 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-1513594

RESUMO

Dried, milled Cestrum laevigatum plant material was drenched to 6 ewes at doses ranging from 2,5 to 10 g/kg/day for 1 to 47 days. The most noticeable clinical signs were depression, anorexia and ruminal stasis. These signs were accompanied by clinical pathological changes indicative of liver involvement such as increases in the serum activities of aspartate transaminase, lactate dehydrogenase and gamma-glutamyltransferase. Hepatosis characterized by accentuated lobulation, and centrilobular to midzonal coagulative necrosis, haemorrhage and congestion occurred in 2 of the 3 ewes given high doses of plant material. Liver lesions in the other animals included disappearance of hepatocytes and collapse of the reticulin stroma in the centrilobular areas. Spongy changes in the cerebral white matter were evident in the ewes of the high-dose group. Ultrastructural changes in the liver comprised degeneration and necrosis of hepatocytes and occasionally endothelial cells, and disruption of sinusoidal walls.


Assuntos
Intoxicação por Plantas/veterinária , Doenças dos Ovinos , Animais , Feminino , Vesícula Biliar/patologia , Fígado/patologia , Intoxicação por Plantas/patologia , Ovinos , Doenças dos Ovinos/patologia
13.
Onderstepoort J Vet Res ; 58(3): 211-21, 1991 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-1923385

RESUMO

The clinical features and pathological findings of 6 steers drenched with dried plant material of Cestrum laevigatum are described. Doses ranging from 0.5 to 10 g/kg/day were given intraruminally for 1 to 38 days. Animals that received 5 to 10 g/kg/day showed nervous signs including ataxia, muscle tremors, hypersensitivity and intermittent chewing. Clinical signs in the steers which received 0,5 to 4 g/kg/day were mild. High doses induced moderate to severe hepatosis characterized by centrilobular to midzonal coagulative necrosis, haemorrhage and congestion. At lower rates only mild hepatic lesions, characterized by disappearance of hepatocytes and collapse of the reticulin stroma in the centrilobular areas were evident. Ultrastructural changes were primarily limited to the hepatocytes and comprised degeneration, necrosis and fatty change. Degeneration and necrosis of endothelial cells and disruption of sinusoidal walls were occasionally observed.


Assuntos
Doenças dos Bovinos/patologia , Intoxicação por Plantas/veterinária , Animais , Bovinos , Doenças dos Bovinos/etiologia , Fígado/patologia , Hepatopatias/patologia , Hepatopatias/veterinária , Masculino , Microscopia Eletrônica , Intoxicação por Plantas/patologia
14.
J S Afr Vet Assoc ; 56(2): 97-8, 1985 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-4020820

RESUMO

Nine feedlot cattle showed clinical signs consistent with those expected in thromboembolic meningoencephalitis. These signs included pyrexia, ataxia, posterior paresis, paralysis and coma. Brown necrotic foci with haemorrhagic borders were observed in the brains of three animals that had died. In these foci vasculitis, thrombosis, infarction and neutrophil infiltration were observed during microscopical examination. Haemophilus somnus was isolated in pure culture from the brains.


Assuntos
Doenças dos Bovinos/epidemiologia , Infecções por Haemophilus/veterinária , Meningoencefalite/veterinária , Tromboembolia/veterinária , Animais , Encéfalo/microbiologia , Encéfalo/patologia , Bovinos , Haemophilus/isolamento & purificação , Infecções por Haemophilus/epidemiologia , Infecções por Haemophilus/microbiologia , Infecções por Haemophilus/patologia , Meningoencefalite/epidemiologia , Meningoencefalite/microbiologia , Meningoencefalite/patologia , África do Sul , Tromboembolia/epidemiologia , Tromboembolia/microbiologia , Tromboembolia/patologia
15.
J S Afr Vet Assoc ; 65(3): 119-21, 1994 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-7595918

RESUMO

Extensive brain pathology attributed to Sarcocystis is described in a heifer and a 2- to 4-month-old calf. These appear to be the first recorded cases of naturally occurring acute sarcocystosis in cattle in sub-Saharan Africa. The heifer became recumbent and had convulsions before dying, while clinical signs in the calf included loss of body mass, diarrhoea, nervousness and opisthotonus. Disseminated haemorrhages were noted in the brains of both animals at necropsy. Microscopically, the grey and white matter contained multiple areas of necrosis associated with haemorrhage, fibrinoid vasculitis, perivascular cuffing and gliosis. A multifocal meningitis was also present. First-generation Sarcocystis schizonts were evident in, or adjacent to endothelial cells of several arterioles and small arteries. The association of first- (as opposed to second-) generation schizogony with overt and fatal bovine sarcocystosis, has not previously been reported.


Assuntos
Doenças dos Bovinos , Encefalite/veterinária , Sarcocistose/veterinária , Animais , Encéfalo/parasitologia , Encéfalo/patologia , Bovinos , Doenças dos Bovinos/parasitologia , Doenças dos Bovinos/patologia , Encefalite/parasitologia , Encefalite/patologia , Feminino , Necrose/veterinária , Sarcocystis/isolamento & purificação , Sarcocistose/complicações , Sarcocistose/parasitologia , Sarcocistose/patologia
16.
Rev Sci Instrum ; 85(4): 045124, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24784676

RESUMO

We demonstrate an optically pumped (87)Rb magnetometer in a microfabricated vapor cell based on a zero-field dispersive resonance generated by optical modulation of the (87)Rb ground state energy levels. The magnetometer is operated in the spin-exchange relaxation-free regime where high magnetic field sensitivities can be achieved. This device can be useful in applications requiring array-based magnetometers where radio frequency magnetic fields can induce cross-talk among adjacent sensors or affect the source of the magnetic field being measured.

17.
Biomed Opt Express ; 3(5): 981-90, 2012 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-22567591

RESUMO

We report on the measurement of somatosensory-evoked and spontaneous magnetoencephalography (MEG) signals with a chip-scale atomic magnetometer (CSAM) based on optical spectroscopy of alkali atoms. The uncooled, fiber-coupled CSAM has a sensitive volume of 0.77 mm(3) inside a sensor head of volume 1 cm(3) and enabled convenient handling, similar to an electroencephalography (EEG) electrode. When positioned over O1 of a healthy human subject, α-oscillations were observed in the component of the magnetic field perpendicular to the scalp surface. Furthermore, by stimulation at the right wrist of the subject, somatosensory-evoked fields were measured with the sensors placed over C3. Higher noise levels of the CSAM were partly compensated by higher signal amplitudes due to the shorter distance between CSAM and scalp.

18.
Rev Sci Instrum ; 82(8): 086112, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21895290

RESUMO

We present magnetic detection of a single, 2 µm diameter cobalt microparticle using an atomic magnetometer based on a microfabricated vapor cell. These results represent an improvement by a factor of 10(5) in terms of the detected magnetic moment over previous work using atomic magnetometers to detect magnetic microparticles. The improved sensitivity is due largely to the use of small vapor cells. In an optimized setup, we predict detection limits of 0.17 µm(3).


Assuntos
Cobalto/química , Magnetometria/métodos , Microtecnologia/métodos , Diamante/química , Nitrogênio/química , Razão Sinal-Ruído , Volatilização
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