Detalhe da pesquisa
1.
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
Nature
; 592(7853): 296-301, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731931
2.
MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia.
Blood
; 139(2): 205-216, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34359073
3.
Linking CRISPR-Cas9 double-strand break profiles to gene editing precision with BreakTag.
Nat Biotechnol
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740992
4.
Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.
J Neurosci
; 32(38): 13111-24, 2012 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993428
5.
Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.
Blood Cancer Discov
; 4(4): 318-335, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067914
6.
Integrative RNA-omics Discovers GNAS Alternative Splicing as a Phenotypic Driver of Splicing Factor-Mutant Neoplasms.
Cancer Discov
; 12(3): 836-855, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34620690
7.
Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs.
Blood Adv
; 6(10): 2992-3005, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35042235
8.
Modeling Leukemia Stem Cells with Patient-Derived Induced Pluripotent Stem Cells.
Methods Mol Biol
; 2185: 411-422, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33165864
9.
Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets.
Cell Stem Cell
; 28(6): 1074-1089.e7, 2021 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571445
10.
Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein.
Sci Rep
; 11(1): 24432, 2021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34952919
11.
Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation.
Blood Adv
; 5(3): 687-699, 2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33560381
12.
Engineering of targeted megabase-scale deletions in human induced pluripotent stem cells.
Exp Hematol
; 87: 25-32, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32544417
13.
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.
Cell Rep
; 31(9): 107688, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32492433
14.
Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.
Cancer Cell
; 36(2): 194-209.e9, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31408619
15.
Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs.
Stem Cell Reports
; 10(5): 1610-1624, 2018 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29681544
16.
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Cell Stem Cell
; 20(3): 315-328.e7, 2017 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215825
17.
LiPS-A3S, a human genomic site for robust expression of inserted transgenes.
Mol Ther Nucleic Acids
; 5(11): e394, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27898090
18.
Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene.
Mol Ther Nucleic Acids
; 5: e284, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26836371
19.
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.
Nat Biotechnol
; 33(6): 646-55, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25798938
20.
SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications.
Leukemia
; 34(9): 2525-2530, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32076118