Detalhe da pesquisa
1.
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Nature
; 585(7824): 277-282, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879489
2.
Targeting allosteric regulation of cancer metabolism.
Nat Chem Biol
; 18(5): 441-450, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484254
3.
A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics.
Metabolomics
; 15(7): 103, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31289941
4.
Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Biochemistry
; 57(47): 6604-6614, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30365304
5.
New tricks for an old drug.
Nat Chem Biol
; 14(11): 990-991, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297874
6.
Hyaluronic acid fuels pancreatic cancer cell growth.
Elife
; 102021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34951587
7.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Nat Commun
; 12(1): 4860, 2021 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381026
8.
Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation.
Cell Stem Cell
; 27(3): 441-458.e10, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610040
9.
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Science
; 368(6486): 85-89, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241947
10.
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.
Cancer Metab
; 8: 1, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31908776
11.
Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS.
Nat Protoc
; 14(2): 313-330, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683937
12.
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Cell Metab
; 29(6): 1390-1399.e6, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827862
13.
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Sci Transl Med
; 11(479)2019 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760578
14.
Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
JCI Insight
; 3(2)2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367463