Detalhe da pesquisa
1.
The impact of aging on primate hematopoiesis as interrogated by clonal tracking.
Blood
; 131(11): 1195-1205, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29295845
2.
Clonal tracking of erythropoiesis in rhesus macaques.
Haematologica
; 105(7): 1813-1824, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582555
3.
Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model.
Mol Ther
; 27(9): 1586-1596, 2019 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253582
4.
Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque.
Mol Ther
; 27(6): 1074-1086, 2019 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31023523
5.
Discordance in lymphoid tissue recovery following stem cell transplantation in rhesus macaques: an in vivo imaging study.
Blood
; 126(24): 2632-41, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26492933
6.
Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques.
Stem Cells
; 33(1): 91-100, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25330775
7.
cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning.
bioRxiv
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464076
8.
Thymidine kinase suicide gene-mediated ganciclovir ablation of autologous gene-modified rhesus hematopoiesis.
Mol Ther
; 20(10): 1932-43, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22910293
9.
High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.
Mol Ther
; 20(10): 1882-92, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22871664
10.
Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques.
Mol Ther Methods Clin Dev
; 28: 62-75, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36620072
11.
Forced enhancer-promoter rewiring to alter gene expression in animal models.
Mol Ther Nucleic Acids
; 31: 452-465, 2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36852088
12.
Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model.
Nat Commun
; 14(1): 6291, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828021
13.
Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation.
Mol Ther Methods Clin Dev
; 29: 483-493, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37273902
14.
Ex vivo expansion of retrovirally transduced primate CD34+ cells results in overrepresentation of clones with MDS1/EVI1 insertion sites in the myeloid lineage after transplantation.
Mol Ther
; 18(9): 1633-9, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20571542
15.
Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models.
Cell Rep Med
; 2(4): 100247, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33948577
16.
Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor.
Sci Transl Med
; 13(591)2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33910976
17.
Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells.
Mol Ther Methods Clin Dev
; 20: 703-715, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33738325
18.
Development of a human immunodeficiency virus type 1-based lentiviral vector that allows efficient transduction of both human and rhesus blood cells.
J Virol
; 83(19): 9854-62, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19625395
19.
Intrabone transplantation of CD34+ cells with optimized delivery does not enhance engraftment in a rhesus macaque model.
Blood Adv
; 4(24): 6148-6156, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351110
20.
BCL11A enhancer-edited hematopoietic stem cells persist in rhesus monkeys without toxicity.
J Clin Invest
; 130(12): 6677-6687, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897878