Detalhe da pesquisa
1.
Polymorphisms in EGFR Gene Predict Clinical Outcome in Unresectable Non-Small Cell Lung Cancer Treated with Radiotherapy and Platinum-Based Chemoradiotherapy.
Int J Mol Sci
; 22(11)2021 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34070597
2.
Transcriptome Analysis of Cells Exposed to Actinomycin D and Nutlin-3a Reveals New Candidate p53-Target Genes and Indicates That CHIR-98014 Is an Important Inhibitor of p53 Activity.
Int J Mol Sci
; 22(20)2021 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681730
3.
PIM2 survival kinase is upregulated in a p53-dependent manner in cells treated with camptothecin or co-treated with actinomycin D and nutlin-3a.
Arch Biochem Biophys
; 655: 26-36, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30096294
4.
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Int J Cancer
; 137(10): 2332-42, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975224
5.
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes.
Chem Biol Interact
; 392: 110946, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460933
6.
Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol.
Mol Biol Rep
; 40(8): 5013-26, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666059
7.
DNA Double-Strand Break Response and Repair Gene Polymorphisms May Influence Therapy Results and Prognosis in Head and Neck Cancer Patients.
Cancers (Basel)
; 15(20)2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894339
8.
Influence of DNA repair gene polymorphisms on prognosis in inoperable non-small cell lung cancer patients treated with radiotherapy and platinum-based chemotherapy.
Int J Cancer
; 131(7): E1100-8, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511383
9.
Germline Variants in Angiogenesis-Related Genes Contribute to Clinical Outcome in Head and Neck Squamous Cell Carcinoma.
Cancers (Basel)
; 14(7)2022 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35406617
10.
A functional analysis of G23A polymorphism and the alternative splicing in the expression of the XPA gene.
Cell Mol Biol Lett
; 15(4): 611-29, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20865363
11.
Association of Genetic Variants in ANGPT/TEK and VEGF/VEGFR with Progression and Survival in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy or Radiochemotherapy.
Cancers (Basel)
; 12(6)2020 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32526933
12.
Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity.
Cell Signal
; 69: 109552, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32032660
13.
The Alzheimer's disease-associated TREM2 gene is regulated by p53 tumor suppressor protein.
Neurosci Lett
; 681: 62-67, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29842899
14.
Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.
Mech Ageing Dev
; 128(11-12): 650-61, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17996922
15.
A novel germline TP53 mutation p.Pro190Arg detected in a patient with lung and bilateral breast cancers.
Adv Med Sci
; 62(2): 207-210, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28499267
16.
Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin.
Cell Signal
; 27(9): 1677-87, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25989210
17.
Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D.
Mech Ageing Dev
; 139: 11-21, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24915467
18.
Functional Impact of Sequence Alterations Found in BRCA1 Promoter/5'UTR Region in Breast/Ovarian Cancer Families from Upper Silesia, Poland.
Hered Cancer Clin Pract
; 4(1): 20-4, 2006 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20222999
19.
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
Mol Carcinog
; 39(3): 155-63, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14991745